Chloroquine phosphate and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chloroquine phosphate (chloroquine phosphate) and Digoxin (digoxin). Common drug interactions include dyspnoea among females and depressed level of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Chloroquine phosphate and Digoxin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Chloroquine phosphate?

Chloroquine phosphate has active ingredients of chloroquine phosphate. It is often used in malaria. eHealthMe is studying from 1,088 Chloroquine phosphate users. Check the latest studies of Chloroquine phosphate.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.



On Aug, 12, 2026

11 people who take Chloroquine phosphate and Digoxin together, and have interactions are studied.

Chloroquine phosphate and Digoxin drug interactions.

What are the common drug interactions of Chloroquine Phosphate and Digoxin, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anaemia (lack of blood)
  3. Visual impairment
  4. Agitation (state of anxiety or nervous excitement)
  5. Arthralgia (joint pain)
  6. Atrioventricular block complete (heart block complete)
  7. Atrophy (wasting away of a part of the body)
  8. Cardiac arrest
  9. Cardiac failure congestive
  10. Cardiomyopathy (weakening of the heart muscle)

male:

  1. Depressed level of consciousness
  2. Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
  3. Spinal compression fracture (fracture due to spinal compression on bone)
  4. Weakness
  5. Abdominal pain
  6. Back pain
  7. Constipation
  8. Methicillin-resistant staphylococcal aureus infection
  9. Myopathy (a muscular disease in which the muscle fibres do not function)
  10. Peripheral neuropathy (damage to nerves of the peripheral nervous system)

What are the common drug interactions of Chloroquine Phosphate and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Alopecia (absence of hair from areas of the body)
  2. Anaemia (lack of blood)
  3. Cardiac failure
  4. Chest pain
  5. Death
  6. Depression
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Diarrhoea
  9. Drug ineffective
  10. Dry eye (lack of adequate tears)

50-59:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anaemia (lack of blood)
  3. Arthralgia (joint pain)
  4. Atrophy (wasting away of a part of the body)
  5. Dyspnoea (difficult or laboured respiration)
  6. Fall
  7. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Increased upper airway secretion
  10. Injection site discolouration

60+:

  1. Atrioventricular block complete (heart block complete)
  2. Cardiac arrest
  3. Ventricular fibrillation (abnormally irregular heart rhythm)
  4. Atherosclerosis (disorder of the arteries)
  5. Back pain
  6. Blood pressure diastolic decreased
  7. Blood pressure systolic increased
  8. Bradycardia (abnormally slow heart action)
  9. Cardiomegaly (increased size of heart than normal)
  10. Cytolytic hepatitis (dissolution or destruction of a liver cell)

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 36.36%
  2. Urination - Painful: 2 people, 18.18%
  3. Cardiac Disorder: 2 people, 18.18%
  4. Chest Pain: 2 people, 18.18%
  5. Depression: 2 people, 18.18%
  6. Dyspnea (difficult or laboured breathing): 2 people, 18.18%
  7. Gastric Disorder (disease of stomach): 2 people, 18.18%
  8. High Blood Pressure: 2 people, 18.18%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 18.18%
  10. Pain: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Chloroquine phosphate and Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chloroquine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Chloroquine phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Digoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on chloroquine phosphate and digoxin (the active ingredients of Chloroquine phosphate and Digoxin, respectively), and Chloroquine phosphate and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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