Chlorthalidone and Erivedge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chlorthalidone (chlorthalidone) and Erivedge (vismodegib). Common drug interactions include ageusia among females and muscle spasms among males.

The phase IV clinical study analyzes what interactions people have when they take Chlorthalidone and Erivedge. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Chlorthalidone?

Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.

What is Erivedge?

Erivedge has active ingredients of vismodegib. eHealthMe is studying from 7,787 Erivedge users. Check the latest studies of Erivedge.



On Jul, 12, 2026

12 people who take Chlorthalidone and Erivedge together, and have interactions are studied.

Chlorthalidone and Erivedge drug interactions.

What are the common drug interactions of Chlorthalidone and Erivedge, by gender? *:

female:

  1. Ageusia (loss of taste functions of the tongue)
  2. Nausea (feeling of having an urge to vomit)
  3. Alopecia (absence of hair from areas of the body)
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Blood sodium decreased
  7. Death
  8. Decreased appetite
  9. Dehydration (dryness resulting from the removal of water)
  10. Diarrhoea

male:

  1. Muscle spasms (muscle contraction)
  2. Alopecia (absence of hair from areas of the body)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Decreased appetite
  6. Abdominal pain upper
  7. Asthenia (weakness)
  8. Cough
  9. Diarrhoea
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Chlorthalidone and Erivedge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Muscle spasms (muscle contraction)
  2. Nausea (feeling of having an urge to vomit)
  3. Pain
  4. Procedural pain
  5. Ageusia (loss of taste functions of the tongue)
  6. Alopecia (absence of hair from areas of the body)
  7. Dysgeusia (disorder of the sense of taste)

60+:

  1. Muscle spasms (muscle contraction)
  2. Alopecia (absence of hair from areas of the body)
  3. Decreased appetite
  4. Abdominal pain upper
  5. Asthenia (weakness)
  6. Diarrhoea
  7. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 11 people, 91.67%
  2. Pain: 1 person, 8.33%
  3. Nausea (feeling of having an urge to vomit): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorthalidone and Erivedge?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Chlorthalidone and Erivedge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chlorthalidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Erivedge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Chlorthalidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Erivedge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlorthalidone and vismodegib (the active ingredients of Chlorthalidone and Erivedge, respectively), and Chlorthalidone and Erivedge (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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