Chlorthalidone and Xopenex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chlorthalidone (chlorthalidone) and Xopenex (levalbuterol hydrochloride). Common drug interactions include cd4 lymphocytes decreased among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Chlorthalidone and Xopenex. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Chlorthalidone?

Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.



On Jul, 14, 2026

55 people who take Chlorthalidone and Xopenex together, and have interactions are studied.

Chlorthalidone and Xopenex drug interactions.

What are the common drug interactions of Chlorthalidone and Xopenex, by gender? *:

female:

  1. Cd4 lymphocytes decreased
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Dehydration (dryness resulting from the removal of water)
  4. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  5. Pneumonia
  6. Ear infection
  7. Fall
  8. Sinusitis (inflammation of sinus)
  9. Dyspnoea (difficult or laboured respiration)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  5. Cataract (clouding of the lens inside the eye)
  6. Dyskinesia (abnormality or impairment of voluntary movement)
  7. Hospitalisation
  8. Infusion related reaction
  9. Insomnia (sleeplessness)
  10. Lung infection

What are the common drug interactions of Chlorthalidone and Xopenex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pneumonia
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Cardiac disorder
  4. Infusion related reaction
  5. Lung infection
  6. Sinusitis (inflammation of sinus)
  7. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

50-59:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  5. Toxoplasma serology positive
  6. Visual disturbance
  7. Vomiting
  8. White blood cells urine positive
  9. Chronic kidney disease
  10. Anaemia (lack of blood)

60+:

  1. Fall
  2. Pneumonia
  3. Scratch
  4. Sinusitis (inflammation of sinus)
  5. Skin atrophy (wasting of skin)
  6. Upper limb fracture
  7. Concussion (short loss of normal brain function in response to a head injury)
  8. Migraine (headache)
  9. Road traffic accident
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 24 people, 43.64%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 12.73%
  3. Primary Immunodeficiency Syndrome: 6 people, 10.91%
  4. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 6 people, 10.91%
  5. High Blood Cholesterol: 5 people, 9.09%
  6. Hypersensitivity: 5 people, 9.09%
  7. Stress And Anxiety: 5 people, 9.09%
  8. Neuralgia (pain in one or more nerves): 5 people, 9.09%
  9. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 9.09%
  10. Diabetes: 5 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Chlorthalidone and Xopenex?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Chlorthalidone and Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chlorthalidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Chlorthalidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlorthalidone and levalbuterol hydrochloride (the active ingredients of Chlorthalidone and Xopenex, respectively), and Chlorthalidone and Xopenex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: