Cholestyramine and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cholestyramine (cholestyramine) and Keppra (levetiracetam). Common drug interactions include gastrooesophageal reflux disease among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Cholestyramine and Keppra. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Cholestyramine?

Cholestyramine has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 9,893 Cholestyramine users. Check the latest studies of Cholestyramine.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 09, 2026

73 people who take Cholestyramine and Keppra together, and have interactions are studied.

Cholestyramine and Keppra drug interactions.

What are the common drug interactions of Cholestyramine and Keppra, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Injection site haematoma (localized swelling filled with blood at injection site)
Injection site haemorrhage (bleeding from injection site)
Nausea (feeling of having an urge to vomit)
Pneumonia
Pulmonary oedema (fluid accumulation in the lungs)
Staphylococcal infection (an infection with staphylococcus bacteria)
Therapeutic response decreased (less preventive response)
Abnormal behaviour

male:

Dyspnoea (difficult or laboured respiration)
Haemoglobin decreased
Haemorrhage intracranial (bleeding within the skull)
Muscular weakness (muscle weakness)
Neutropenia (an abnormally low number of neutrophils)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Swelling face
Thrombocytopenia (decrease of platelets in blood)
Blood pressure increased

What are the common drug interactions of Cholestyramine and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hyperammonaemia
Urinary tract infection

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Haemorrhage intracranial (bleeding within the skull)
Abdominal pain
Bile acid malabsorption
Blood pressure increased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Hydrocephalus (water on the brain)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nasopharyngitis (inflammation of the nasopharynx)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall
Haemoglobin decreased
Neutropenia (an abnormally low number of neutrophils)
Pain in extremity
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Multiple myeloma (cancer of the plasma cells)
Death
Monoclonal immunoglobulin present

50-59:

Hypertension (high blood pressure)
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyspnoea (difficult or laboured respiration)
Muscular weakness (muscle weakness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Swelling face
Acne (skin problems that cause pimples)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

60+:

Weight decreased
Headache (pain in head)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Pneumonia
Pyrexia (fever)
Renal failure (kidney dysfunction)
Adverse drug reaction
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Asthenia (weakness)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 15.07%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 12.33%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 10.96%
Nausea (feeling of having an urge to vomit): 8 people, 10.96%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 8 people, 10.96%
Stress And Anxiety: 7 people, 9.59%
Pain: 7 people, 9.59%
High Blood Cholesterol: 6 people, 8.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.22%
Breakthrough Pain: 5 people, 6.85%

* Approximation only. Some reports may have incomplete information.

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