Cialis and Robitussin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cialis (tadalafil) and Robitussin (guaifenesin). Common drug interactions include cough among females and arteriovenous fistula occlusion among males.

The phase IV clinical study analyzes what interactions people have when they take Cialis and Robitussin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Cialis?

Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 28,532 Cialis users. Check the latest studies of Cialis.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

On Jul, 15, 2026

18 people who take Cialis and Robitussin together, and have interactions are studied.

Cialis and Robitussin drug interactions.

What are the common drug interactions of Cialis and Robitussin, by gender? *:

female:

Cough
Oropharyngeal pain

male:

Arteriovenous fistula occlusion
Anaemia (lack of blood)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nerve root injury lumbar (nerve root injury at the lumber vertebra)
Neuropathy peripheral (surface nerve damage)
Nightmare (unpleasant dream)
Pancreatitis (inflammation of pancreas)
Paralysis
Pericardial effusion (fluid around the heart)

What are the common drug interactions of Cialis and Robitussin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cough
Oropharyngeal pain

30-39:

n/a

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Neuropathy peripheral (surface nerve damage)
Pancreatitis (inflammation of pancreas)
Paralysis
Road traffic accident
Swelling
Syringomyelia (cavity forms within the spinal cord)
Type 2 diabetes mellitus

50-59:

Anaemia (lack of blood)
Arteriovenous fistula occlusion
Dyspnoea (difficult or laboured respiration)
Chronic kidney disease
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Renal failure (kidney dysfunction)

60+:

Arteriovenous fistula occlusion
Overdose
Pericardial effusion (fluid around the heart)
Pericarditis (inflammation of the pericardium)
Plasma cell myeloma (cancer that begins in plasma cells)
Pleural effusion (water on the lungs)
Vascular calcification (deposits of calcium in the blood vessels)
Dehydration (dryness resulting from the removal of water)
Asthenia (weakness)
Decreased appetite

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 44.44%
Depression: 7 people, 38.89%
High Blood Pressure: 6 people, 33.33%
Cough: 6 people, 33.33%
Constipation: 5 people, 27.78%
Insomnia (sleeplessness): 5 people, 27.78%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 4 people, 22.22%
Bipolar Disorder (mood disorder): 4 people, 22.22%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 22.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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