Cider vinegar and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cider vinegar (apple cider vinegar) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include back pain among females and akathisia among males.

The phase IV clinical study analyzes what interactions people have when they take Cider vinegar and Hydroxyzine. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Cider vinegar?

Cider vinegar has active ingredients of apple cider vinegar. It is often used in weight loss. eHealthMe is studying from 1,517 Cider vinegar users. Check the latest studies of Cider vinegar.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

37 people who take Cider vinegar and Hydroxyzine together, and have interactions are studied.

Cider vinegar and Hydroxyzine drug interactions.

What are the common drug interactions of Cider Vinegar and Hydroxyzine, by gender? *:

female:

Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Fatigue (feeling of tiredness)
Fungal infection
Influenza
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Sleep disorder
Abdominal discomfort
Anaphylactic reaction (serious allergic reaction)

male:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Cider Vinegar and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Fungal infection
Localised infection (infection at the single location)
Osteoporosis (bones weak and more likely to break)
Staphylococcal skin infection (skin infection by an infection with staphylococcus bacteria)
Vomiting

10-19:

Fibromyalgia (a long-term condition which causes pain all over the body)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Wisdom teeth removal

20-29:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)

30-39:

Back pain
Cough
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Folliculitis (infection of hair root)
Fungal infection
Headache (pain in head)
Influenza
Malaise (a feeling of general discomfort or uneasiness)
Mastitis (inflammation of breast)

40-49:

Hospitalisation
Initial insomnia (feeling of inadequate or poor-quality sleep)
Lung disorder (lung disease)
Oropharyngeal pain
Quality of life decreased
Respiratory tract congestion (blockage on respiratory system)
Skin fissures (a crack in the skin)
Substance-induced psychotic disorder
Upper-airway cough syndrome
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Nausea (feeling of having an urge to vomit)
Surgery
Abdominal pain upper
Acne (skin problems that cause pimples)
Ageusia (loss of taste functions of the tongue)
Anosmia (partial or complete loss of the sense of smell)
Asthenia (weakness)
Diarrhoea
Drug intolerance (drug sensitivity)
Dyspepsia (indigestion)

60+:

Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Single functional kidney (single kidney)
Urinary casts
Urinary sediment present
Urine abnormality
Urine leukocyte esterase positive
Urine protein/creatinine ratio increased
White blood cells urine positive
Adverse event

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 18.92%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 16.22%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 13.51%
Pain: 3 people, 8.11%
Migraine (headache): 3 people, 8.11%
Immunodeficiency Common Variable: 3 people, 8.11%
Immunodeficiency: 3 people, 8.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.41%
Muscle Aches (muscle pain): 2 people, 5.41%
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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