Cilostazol and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cilostazol (cilostazol) and Prograf (tacrolimus). Common drug interactions include cystitis among females and renal injury among males.

The phase IV clinical study analyzes what interactions people have when they take Cilostazol and Prograf. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Cilostazol?

Cilostazol has active ingredients of cilostazol. It is often used in arteriosclerosis of the extremities. eHealthMe is studying from 7,877 Cilostazol users. Check the latest studies of Cilostazol.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.



On Jul, 10, 2026

46 people who take Cilostazol and Prograf together, and have interactions are studied.

Cilostazol and Prograf drug interactions.

What are the common drug interactions of Cilostazol and Prograf, by gender? *:

female:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Dyslipidaemia (abnormal amount of lipids)
  3. Fatigue (feeling of tiredness)
  4. Fear of disease
  5. Headache (pain in head)
  6. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  7. Hyperlipidaemia (presence of excess lipids in the blood)
  8. Hyperthermia (body temperature greatly above normal)
  9. Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
  10. Nephrogenic anaemia (anaemia due to kidney disease)

male:

  1. Renal injury (kidney injury)
  2. Pneumonia
  3. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  4. Fall
  5. Injury
  6. Muscle haemorrhage (bleeding in muscle)
  7. Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Urinary tract infection
  10. Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Cilostazol and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaemia (lack of blood)
  2. Appendicitis (inflammation of the appendix)
  3. Back pain
  4. Chronic kidney disease
  5. Cough
  6. Cystitis (inflammation of the wall of the bladder)
  7. Dehydration (dryness resulting from the removal of water)
  8. Diarrhoea
  9. Dyslipidaemia (abnormal amount of lipids)
  10. Gastroenteritis (inflammation of stomach and intestine)

30-39:

  1. Acute tonsillitis
  2. Constipation
  3. Cough
  4. Dental caries
  5. Dermatitis allergic (inflammation of the skin due allergic reaction)
  6. Diarrhoea
  7. Dizziness
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  9. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  10. Gallbladder injury

40-49:

n/a

50-59:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Asthenia (weakness)
  6. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  7. Joint range of motion decreased (disease of joint movement)
  8. Mobility decreased (ability to move is reduced)
  9. Muscle tightness
  10. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

60+:

  1. Pneumonia
  2. Gastrointestinal necrosis (destruction of gastrointestinal organ)
  3. Injury
  4. Muscle haemorrhage (bleeding in muscle)
  5. Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Urinary tract infection
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Visual acuity reduced (reduced clearness of vision)
  10. Visual impairment

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 21.74%
  2. Nuclear Magnetic Resonance Imaging Abdominal: 9 people, 19.57%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 15.22%
  4. Diabetes: 7 people, 15.22%
  5. Nuclear Magnetic Resonance Imaging Brain: 5 people, 10.87%
  6. Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 10.87%
  7. Kidney Transplant Rejection: 5 people, 10.87%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.70%
  9. Pain: 4 people, 8.70%
  10. High Blood Cholesterol: 4 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Cilostazol and Prograf?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cilostazol and Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cilostazol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cilostazol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prograf and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cilostazol and tacrolimus (the active ingredients of Cilostazol and Prograf, respectively), and Cilostazol and Prograf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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