Cimetidine and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cimetidine (cimetidine) and Astelin (azelastine hydrochloride). Common drug interactions include fatigue among females and coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Astelin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.



On Jul, 28, 2026

18 people who take Cimetidine and Astelin together, and have interactions are studied.

Cimetidine and Astelin drug interactions.

What are the common drug interactions of Cimetidine and Astelin, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Arthralgia (joint pain)
  4. Back pain
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Dependence
  7. Drug abuse
  8. Drug ineffective
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Eating disorder

male:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Crying
  3. Anxiety
  4. Confusional state
  5. Heart injury
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Pain
  8. Chronic kidney disease
  9. Renal failure (kidney dysfunction)
  10. Depressed mood

What are the common drug interactions of Cimetidine and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Crying
  2. Depressed mood
  3. Dizziness
  4. Dry mouth
  5. Hallucination (an experience involving the perception of something not present)
  6. Impaired healing
  7. Tension (the act or process of stretching something tight)
  8. Vision blurred
  9. Confusional state
  10. Hypoaesthesia (reduced sense of touch or sensation)

40-49:

  1. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  2. Dependence
  3. Drug abuse
  4. Drug ineffective
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Eating disorder
  7. Fall
  8. Fatigue (feeling of tiredness)
  9. Gait disturbance
  10. Hallucination (an experience involving the perception of something not present)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

60+:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Anxiety
  4. Heart injury
  5. Pain

What are the existing conditions these people have? *

  1. High Blood Pressure: 7 people, 38.89%
  2. Pain: 6 people, 33.33%
  3. Urinary Tract Infection: 5 people, 27.78%
  4. Mixed Incontinence (a combination of stress and urge incontinence): 5 people, 27.78%
  5. Depression: 5 people, 27.78%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 27.78%
  7. Hypertriglyceridaemia (excess of triglycerides in the blood): 5 people, 27.78%
  8. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 27.78%
  9. Insomnia (sleeplessness): 5 people, 27.78%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 27.78%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cimetidine and Astelin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Astelin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cimetidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Astelin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cimetidine and azelastine hydrochloride (the active ingredients of Cimetidine and Astelin, respectively), and Cimetidine and Astelin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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