Cimetidine and Codeine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cimetidine (cimetidine) and Codeine sulfate (codeine sulfate). Common drug interactions include melanocytic naevus among females and colon cancer among males.

The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Codeine sulfate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.



On Jul, 11, 2026

13 people who take Cimetidine and Codeine sulfate together, and have interactions are studied.

Cimetidine and Codeine sulfate drug interactions.

What are the common drug interactions of Cimetidine and Codeine Sulfate, by gender? *:

female:

  1. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  2. Death
  3. Dizziness
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  6. Headache (pain in head)
  7. Pain in extremity
  8. Pruritus (severe itching of the skin)
  9. Abdominal pain
  10. Asthenia (weakness)

male:

  1. Colon cancer
  2. Fatigue (feeling of tiredness)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Cimetidine and Codeine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Depression
  2. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  3. Diabetes mellitus inadequate control
  4. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  5. Diabetic nephropathy (diabetic kidney disease)
  6. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  7. Diastolic dysfunction
  8. Drug hypersensitivity
  9. Dyspepsia (indigestion)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

50-59:

  1. Death
  2. Cardiac arrest
  3. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

60+:

  1. Hypertension (high blood pressure)
  2. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  3. Benign breast neoplasm (benign (non-cancerous) tumours of the breast)
  4. Blood pressure increased
  5. Cardiac failure congestive
  6. Carpal tunnel decompression
  7. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Chronic gastritis (long lasting infection of stomach lining)
  10. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 23.08%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 23.08%
  3. Back Pain: 2 people, 15.38%
  4. Bone Disorder: 2 people, 15.38%
  5. Gout (uric acid crystals building up in the body): 2 people, 15.38%
  6. Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
  7. Vulvovaginal Dryness: 1 person, 7.69%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
  9. Cough: 1 person, 7.69%
  10. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cimetidine and Codeine sulfate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cimetidine and Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cimetidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cimetidine and codeine sulfate (the active ingredients of Cimetidine and Codeine sulfate, respectively), and Cimetidine and Codeine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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