Cimetidine and Colchicine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cimetidine (cimetidine) and Colchicine (colchicine). Common drug interactions include peripheral swelling among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Colchicine. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

On Jul, 10, 2026

60 people who take Cimetidine and Colchicine together, and have interactions are studied.

Cimetidine and Colchicine drug interactions.

What are the common drug interactions of Cimetidine and Colchicine, by gender? *:

female:

Peripheral swelling
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Vomiting
Fatigue (feeling of tiredness)
Pyrexia (fever)
Headache (pain in head)
Infection
Urticaria (rash of round, red welts on the skin that itch intensely)
Conjunctivitis (pink eye)
Malaise (a feeling of general discomfort or uneasiness)

male:

Chronic kidney disease
Abdominal pain
Headache (pain in head)
Abdominal discomfort
Anaemia (lack of blood)
Anaemia of malignant disease
Anaemia vitamin b12 deficiency
Anxiety
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Cimetidine and Colchicine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
C-reactive protein increased
Malaise (a feeling of general discomfort or uneasiness)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pyrexia (fever)

30-39:

Decreased activity
Decreased appetite
Decreased interest
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Drug ineffective
Dry eye (lack of adequate tears)
Dry mouth
Fatigue (feeling of tiredness)
Gingival swelling (gums swelling)

40-49:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Alopecia (absence of hair from areas of the body)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Headache (pain in head)
Infection
Psoriasis (immune-mediated disease that affects the skin)
Upper respiratory tract infection
Vomiting
Eye inflammation

50-59:

Chronic kidney disease
Arthralgia (joint pain)
C-reactive protein increased
Conjunctivitis (pink eye)
Deafness
Deafness neurosensory
Ear congestion
Eye irritation
Fatigue (feeling of tiredness)
Gait disturbance

60+:

Chronic kidney disease
Anxiety
Nephrogenic anaemia (anaemia due to kidney disease)
Dizziness
Fall
Head injury
Hyperhidrosis (abnormally increased sweating)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Angioedema (rapid swelling of the dermis)
Back pain

What are the existing conditions these people have? *

Pain: 17 people, 28.33%
High Blood Pressure: 15 people, 25.00%
Infection: 11 people, 18.33%
Chest Pain: 10 people, 16.67%
Inflammation: 10 people, 16.67%
High Blood Cholesterol: 9 people, 15.00%
Type 2 Diabetes: 8 people, 13.33%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 7 people, 11.67%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 10.00%
Depression: 6 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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