Cimetidine and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cimetidine (cimetidine) and Fentanyl citrate (fentanyl citrate). Common drug interactions include dysphagia among females and alanine aminotransferase increased among males.
The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Fentanyl citrate. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Cimetidine?
Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.
What is Fentanyl citrate?
Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.
17 people who take Cimetidine and Fentanyl citrate together, and have interactions are studied.

What are the common drug interactions of Cimetidine and Fentanyl Citrate, by gender? *:
female:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Hepatic enzyme increased
- Hepatomegaly (abnormal enlargement of the liver)
- Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
- Infection
- Intestinal obstruction
- Metastatic neoplasm (spreadable cancer tumour)
- Neutropenia (an abnormally low number of neutrophils)
male:
- Alanine aminotransferase increased
- Alopecia (absence of hair from areas of the body)
- Chest pain
- Chills (felling of cold)
- Decreased interest
- Dental caries
- Depression
- Dysuria (painful or difficult urination)
- Erectile dysfunction
- Fatigue (feeling of tiredness)
What are the common drug interactions of Cimetidine and Fentanyl Citrate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal distension
- Abdominal pain
- Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Collapse of lung (functional breakdown of lung)
- Constipation
- Culture urine positive
- Dyspnoea (difficult or laboured respiration)
- Intestinal obstruction
- Metastatic neoplasm (spreadable cancer tumour)
30-39:
n/a
40-49:
- Urinary tract infection
- Urine flow decreased
- Vomiting
- Chronic kidney disease
- Metastases to liver (cancer spreads to liver)
- Renal injury (kidney injury)
- Alanine aminotransferase increased
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Asthenia (weakness)
50-59:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Metastases to spine (cancer spreads to spine)
- Respiratory depression (respiration has a rate below 12 breaths)
- Aphasia (damage to the parts of the brain that control language)
- Cardiac disorder
- Chronic hepatic failure (long lasting liver failure)
- Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
- Diaphragmatic paralysis (acquired dysfunction of the phrenic nerve)
- Dysphagia (a condition in which swallowing is difficult or painful)
60+:
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Abdominal pain
- Hepatic enzyme increased
- Infection
- Nausea (feeling of having an urge to vomit)
- Neutropenia (an abnormally low number of neutrophils)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Po2 decreased
- Thrombocytopenia (decrease of platelets in blood)
- Vomiting
What are the existing conditions these people have? *
- Gastric Ulcer (stomach ulcer): 3 people, 17.65%
- Weakness: 2 people, 11.76%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 11.76%
- Cancer Pain: 2 people, 11.76%
- Epidural Anaesthesia: 2 people, 11.76%
- Hypoaesthesia (reduced sense of touch or sensation): 2 people, 11.76%
- Prostate Cancer: 2 people, 11.76%
- Nausea (feeling of having an urge to vomit): 1 person, 5.88%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 5.88%
- Abdominal Pain Upper: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Cimetidine and Fentanyl citrate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cimetidine (10,531 reports)
- Fentanyl citrate (21,294 reports)
Browse all drug interactions of Cimetidine and Fentanyl citrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cimetidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fentanyl citrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cimetidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fentanyl citrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cimetidine and fentanyl citrate (the active ingredients of Cimetidine and Fentanyl citrate, respectively), and Cimetidine and Fentanyl citrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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