Cimetidine and Restasis drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cimetidine (cimetidine) and Restasis (cyclosporine). Common drug interactions include diarrhoea among females.
The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Restasis. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Cimetidine?
Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
22 people who take Cimetidine and Restasis together, and have interactions are studied.

What are the common drug interactions of Cimetidine and Restasis, by gender? *:
female:
- Diarrhoea
- Pain
- Drug hypersensitivity
- Muscle tightness
- Nausea (feeling of having an urge to vomit)
- Rash
- Sinusitis (inflammation of sinus)
- Skin cancer
- Vomiting
- Accident
male:
n/a
What are the common drug interactions of Cimetidine and Restasis, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Blood pressure increased
- Cardiac flutter (abnormal heart rhythm)
- Chest pain
- Heart rate increased
50-59:
- Pain
- Abdominal pain
- Accident
- Contusion (a type of hematoma of tissue in which capillaries)
- Cough
- Diarrhoea
- Fall
- Fatigue (feeling of tiredness)
- Gastrointestinal bacterial infection (infection of the stomach and intestines caused by bacteria)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
60+:
- Diarrhoea
- Fatigue (feeling of tiredness)
- Infection
- Limb injury
- Localised infection (infection at the single location)
- Memory impairment
- Nasopharyngitis (inflammation of the nasopharynx)
- Nausea (feeling of having an urge to vomit)
- Rash
- Scapula fracture (a fracture of the scapula, the shoulder blade)
What are the existing conditions these people have? *
- Sleep Disorder: 6 people, 27.27%
- High Blood Pressure: 5 people, 22.73%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 5 people, 22.73%
- High Blood Cholesterol: 5 people, 22.73%
- Insomnia (sleeplessness): 5 people, 22.73%
- Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 18.18%
- Infection: 4 people, 18.18%
- Pain: 4 people, 18.18%
- Neuralgia (pain in one or more nerves): 4 people, 18.18%
- Immunodeficiency Common Variable: 4 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Cimetidine and Restasis?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cimetidine (10,531 reports)
- Restasis (35,199 reports)
Browse all drug interactions of Cimetidine and Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cimetidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cimetidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cimetidine and cyclosporine (the active ingredients of Cimetidine and Restasis, respectively), and Cimetidine and Restasis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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