Cimzia and Dyazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cimzia (certolizumab pegol) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include insomnia among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Cimzia and Dyazide. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Cimzia?

Cimzia has active ingredients of certolizumab pegol. It is often used in rheumatoid arthritis. eHealthMe is studying from 106,745 Cimzia users. Check the latest studies of Cimzia.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.

On Aug, 10, 2026

30 people who take Cimzia and Dyazide together, and have interactions are studied.

What are the common drug interactions of Cimzia and Dyazide, by gender? *:

female:

Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Weight decreased
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Antinuclear antibody positive
Anxiety
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Butterfly rash
Cardiac murmur (an heart sound in valve abnormality)
Cardiovascular disorder (heart diseases)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Oesophageal candidiasis (fungal infection of oesophagus)

What are the common drug interactions of Cimzia and Dyazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypersensitivity
Rash pruritic (redness with itching)
Myalgia (muscle pain)
Swelling face
Asthenia (weakness)
Insomnia (sleeplessness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neurological symptom (symptoms of nervous system disease)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)

40-49:

Arthralgia (joint pain)
Oesophageal candidiasis (fungal infection of oesophagus)

50-59:

Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Anaemia (lack of blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Influenza like illness
Nausea (feeling of having an urge to vomit)
Weight decreased
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Alopecia (absence of hair from areas of the body)
Antinuclear antibody positive

60+:

Urinary tract infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective
Fall
Foot fracture
Frequent bowel movements
Gait disturbance
Gastrointestinal hypomotility (less activity of the intestinal tract)
Injection site reaction

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 40.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 23.33%
Pain: 5 people, 16.67%
Insomnia (sleeplessness): 5 people, 16.67%
High Blood Cholesterol: 4 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 13.33%
Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 10.00%
Stress And Anxiety: 3 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%
Hypersensitivity: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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