Clarithromycin and Asacol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Asacol (mesalamine). Common drug interactions include pain among females and agitation among males.
The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Asacol. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Clarithromycin?
Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.
What is Asacol?
Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.
25 people who take Clarithromycin and Asacol together, and have interactions are studied.

What are the common drug interactions of Clarithromycin and Asacol, by gender? *:
female:
- Pain
- Drug hypersensitivity
- Diarrhoea
- Dysgeusia (disorder of the sense of taste)
- Gingival ulceration (ulcer on gums)
- Mouth ulceration (mouth ulcers)
- Nausea (feeling of having an urge to vomit)
- Oral mucosal blistering (mouth ulcer)
- Tongue ulceration (ulcers on tongue)
- Chronic kidney disease
male:
- Agitation (state of anxiety or nervous excitement)
- Rash macular (small, flat red spots)
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Nerve injury
- Pain
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Scar
- Scrotal abscess (pus in scrotum)
What are the common drug interactions of Clarithromycin and Asacol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood creatine phosphokinase increased
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Acute pulmonary histoplasmosis (acute infection by inhalation of spores of the fungus histoplasma capsulatum)
20-29:
n/a
30-39:
n/a
40-49:
- Pain
- Anxiety
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Deformity (disfigurement)
- Emotional distress
- Fear
- Haematochezia (passage of stools containing blood)
- Hospitalisation
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
50-59:
- Respiratory tract infection
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bone density decreased
- Bone disorder
- Calcium deficiency (lack of calcium)
- Drug ineffective
- Hypertension (high blood pressure)
- Migraine (headache)
- Multiple fractures
60+:
- Diarrhoea
- Dysgeusia (disorder of the sense of taste)
- Coagulopathy (blood's ability to clot is impaired)
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
- Gingival ulceration (ulcer on gums)
- Mouth ulceration (mouth ulcers)
- Nausea (feeling of having an urge to vomit)
- Oral mucosal blistering (mouth ulcer)
- Pain
What are the existing conditions these people have? *
- Infection: 5 people, 20.00%
- Depression: 4 people, 16.00%
- Hypersensitivity: 3 people, 12.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
- Stress And Anxiety: 2 people, 8.00%
- Renal Disorder (kidney disease): 2 people, 8.00%
- Pain: 2 people, 8.00%
- Multiple Allergies (allergy to multiple agents): 2 people, 8.00%
- Indigestion: 2 people, 8.00%
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Clarithromycin and Asacol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clarithromycin (45,044 reports)
- Asacol (20,618 reports)
Browse all drug interactions of Clarithromycin and Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clarithromycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clarithromycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Asacol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clarithromycin and mesalamine (the active ingredients of Clarithromycin and Asacol, respectively), and Clarithromycin and Asacol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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