Clarithromycin and Cefoxitin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Cefoxitin (cefoxitin sodium). Common drug interactions include leukocytoclastic vasculitis among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Cefoxitin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Cefoxitin?

Cefoxitin has active ingredients of cefoxitin sodium. eHealthMe is studying from 611 Cefoxitin users. Check the latest studies of Cefoxitin.

On Aug, 12, 2026

45 people who take Clarithromycin and Cefoxitin together, and have interactions are studied.

Clarithromycin and Cefoxitin drug interactions.

What are the common drug interactions of Clarithromycin and Cefoxitin, by gender? *:

female:

Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Drug ineffective
Lip swelling
Nausea (feeling of having an urge to vomit)
Rash
General physical health deterioration (weak health status)
Abdominal pain
Drug level increased
Erythema (redness of the skin)
Lipase increased

male:

Thrombocytopenia (decrease of platelets in blood)
Neutropenia (an abnormally low number of neutrophils)
Dyspnoea (difficult or laboured respiration)
Haematuria (presence of blood in urine)
Lactic acidosis (low ph in body tissues)
Nausea (feeling of having an urge to vomit)
Pancreatitis acute (sudden inflammation of pancreas)
Pulmonary haemorrhage (acute bleeding from the lung)
Acute respiratory failure
Ankle fracture

What are the common drug interactions of Clarithromycin and Cefoxitin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Death

10-19:

Abdominal pain
Chest pain
Drug ineffective
Pancreatitis acute (sudden inflammation of pancreas)
Pulmonary haemorrhage (acute bleeding from the lung)
Deafness neurosensory
Pleural effusion (water on the lungs)
Cough
Dyspnoea (difficult or laboured respiration)
Neutropenia (an abnormally low number of neutrophils)

20-29:

Abdominal pain
Drug level increased
Haematuria (presence of blood in urine)
Lipase increased
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Thrombocytopenia (decrease of platelets in blood)
Vomiting
Anaphylactic reaction (serious allergic reaction)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)

30-39:

Nephropathy toxic (damage to kidney due to toxins)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)
Renal injury (kidney injury)
Erythema (redness of the skin)
Lip swelling
Pallor
Swelling face
Swollen tongue (swelling of tongue)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Drug intolerance (drug sensitivity)
Thrombocytopenia (decrease of platelets in blood)
Paradoxical drug reaction
Alanine aminotransferase increased
Aspartate aminotransferase increased
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pulmonary tuberculosis (lungs tuberculosis)

50-59:

Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Rash

60+:

Drug ineffective
General physical health deterioration (weak health status)
Hepatotoxicity (chemical-driven liver damage)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Pleuritic pain
Thrombocytopenia (decrease of platelets in blood)
Tinnitus (a ringing in the ears)
Renal failure acute (rapid kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

Mycobacterium Abscessus Infection (rapid growing bacterial infection): 18 people, 40.00%
Mycobacterial Infection: 9 people, 20.00%
Mycobacterium Chelonae Infection (bacterial infection): 5 people, 11.11%
Lung Infection: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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