Clarithromycin and Excedrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Excedrin (acetaminophen; aspirin; caffeine). Common drug interactions include chronic kidney disease among females.

The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Excedrin. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.



On Aug, 02, 2026

30 people who take Clarithromycin and Excedrin together, and have interactions are studied.

Clarithromycin and Excedrin drug interactions.

What are the common drug interactions of Clarithromycin and Excedrin, by gender? *:

female:

  1. Chronic kidney disease
  2. Anxiety
  3. Hepatic failure (liver failure)
  4. Humerus fracture (injury to the upper arm bone)
  5. Kidney infection
  6. Maternal exposure before pregnancy (use of substance before pregnancy)
  7. Maternal exposure during pregnancy (use of substance during pregnancy)
  8. Multiple fractures
  9. Nervousness
  10. Oedema peripheral (superficial swelling)

male:

n/a

What are the common drug interactions of Clarithromycin and Excedrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anogenital warts
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Blood hiv rna increased
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Depression
  7. Humerus fracture (injury to the upper arm bone)
  8. Kidney infection
  9. Maternal exposure before pregnancy (use of substance before pregnancy)
  10. Maternal exposure during pregnancy (use of substance during pregnancy)

40-49:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Nausea (feeling of having an urge to vomit)
  3. Pain in extremity
  4. Weight decreased
  5. Chronic kidney disease
  6. Dizziness
  7. Fatigue (feeling of tiredness)
  8. Feeding disorder (when children refuse to eat certain food groups)
  9. Feeling drunk
  10. Gallbladder operation

50-59:

  1. Death
  2. Hepatic failure (liver failure)

60+:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. White blood cell count decreased

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 33.33%
  2. Hypersensitivity: 9 people, 30.00%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 26.67%
  4. High Blood Pressure: 8 people, 26.67%
  5. Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 23.33%
  6. Infection: 7 people, 23.33%
  7. Cough: 7 people, 23.33%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 23.33%
  9. Migraine (headache): 7 people, 23.33%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 23.33%

* Approximation only. Some reports may have incomplete information.

Do you take Clarithromycin and Excedrin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clarithromycin and Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clarithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clarithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Excedrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clarithromycin and acetaminophen; aspirin; caffeine (the active ingredients of Clarithromycin and Excedrin, respectively), and Clarithromycin and Excedrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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