Clarithromycin and Iressa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Iressa (gefitinib). Common drug interactions include neutropenia among females and intestinal obstruction among males.

The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Iressa. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Iressa?

Iressa has active ingredients of gefitinib. eHealthMe is studying from 10,102 Iressa users. Check the latest studies of Iressa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

24 people who take Clarithromycin and Iressa together, and have interactions are studied.

Clarithromycin and Iressa drug interactions.

What are the common drug interactions of Clarithromycin and Iressa, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Cardiac tamponade (fluid accumulates in heart covering)
Cardiomegaly (increased size of heart than normal)
Leukopenia (less number of white blood cells in blood)
Pericardial effusion (fluid around the heart)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Alanine aminotransferase increased
Aspartate aminotransferase increased

male:

Intestinal obstruction
Decreased appetite
Respiratory failure (inadequate gas exchange by the respiratory system)
Dysgeusia (disorder of the sense of taste)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angiopathy (generic term for a disease of the blood vessels)
Asthenia (weakness)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Blood pressure decreased
Diarrhoea

What are the common drug interactions of Clarithromycin and Iressa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cardiac tamponade (fluid accumulates in heart covering)
Cardiomegaly (increased size of heart than normal)
Neutropenia (an abnormally low number of neutrophils)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Hepatic function abnormal

50-59:

Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Lung disorder (lung disease)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Renal disorder (kidney disease)

60+:

Dysgeusia (disorder of the sense of taste)
Intestinal obstruction
Pneumonia bacterial (pneumonia associated with bacterial infection)
Renal impairment (severely reduced kidney function)
Respiratory failure (inadequate gas exchange by the respiratory system)
Interstitial lung disease
Malignant neoplasm progression (cancer tumour came back)
Metastases to bone (cancer spreads to bone)
Metastases to central nervous system (cancer spreads to central nervous system)
Metastases to lymph nodes (cancer spreads to lymph node)

What are the existing conditions these people have? *

Lung Adenocarcinoma (a form of non-small cell lung cancer): 6 people, 25.00%
Pneumonia: 5 people, 20.83%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 20.83%
Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 16.67%
Insomnia (sleeplessness): 4 people, 16.67%
High Blood Pressure: 4 people, 16.67%
Gastric Ulcer (stomach ulcer): 4 people, 16.67%
Constipation: 4 people, 16.67%
Psychosomatic Disease (situation in which the mind influences the body to create or complicate an illness): 3 people, 12.50%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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