Clarithromycin and Propulsid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Propulsid (cisapride monohydrate). Common drug interactions include cataract among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Propulsid. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Clarithromycin?
Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.
What is Propulsid?
Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.
31 people who take Clarithromycin and Propulsid together, and have interactions are studied.

What are the common drug interactions of Clarithromycin and Propulsid, by gender? *:
female:
- Cataract (clouding of the lens inside the eye)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Congestive cardiomyopathy (weakening of heart muscle)
- Corneal abrasion (loss of the surface of cornea)
- Culture urine positive
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus inadequate control
- Diarrhoea
- Drug abuse
- Drug toxicity
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Fear of disease
- Aspartate aminotransferase increased
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood alkaline phosphatase increased
- Blood glucose increased
- Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Cardiac arrest
- Cardiac disorder
What are the common drug interactions of Clarithromycin and Propulsid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Apnoea (suspension of external breathing)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Cardiac arrest
- Digoxin toxicity
- Drug abuse
- Electrocardiogram qt prolonged
- Gastroenteritis helicobacter (inflammation of stomach and intestine caused by helicobacter infection)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypokalaemia (low potassium)
- Migraine (headache)
10-19:
n/a
20-29:
n/a
30-39:
- Arrhythmia (irregular heartbeat)
- Cardiac disorder
- Electrocardiogram qt prolonged
- Heart rate irregular
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arrhythmia (irregular heartbeat)
- Back pain
- Cardiac disorder
- Chest pain
- Drug abuse
- Electrocardiogram qt prolonged
- Flushing (the warm, red condition of human skin)
- Heart rate increased
50-59:
- Diabetes mellitus inadequate control
- Dry eye (lack of adequate tears)
- Dyskinesia oesophageal (abnormality or impairment of voluntary movement of oesophageal)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Epistaxis (bleed from the nose)
- Escherichia infection (bacterial infection by escherichia coli)
- Eye injury
- Eyelid ptosis (falling of the upper or lower eyelid)
- Faeces discoloured
- Fatigue (feeling of tiredness)
60+:
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Chest pain
- Blood magnesium decreased
- Bradycardia (abnormally slow heart action)
- Cardiac disorder
- Cholecystitis (infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Chronic obstructive airways disease
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Gastric ulcer (stomach ulcer)
* Approximation only. Some reports may have incomplete information.
Do you take Clarithromycin and Propulsid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clarithromycin (45,044 reports)
- Propulsid (8,130 reports)
Browse all drug interactions of Clarithromycin and Propulsid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clarithromycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Propulsid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clarithromycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Propulsid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on clarithromycin and cisapride monohydrate (the active ingredients of Clarithromycin and Propulsid, respectively), and Clarithromycin and Propulsid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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