Clarithromycin and Restoril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Restoril (temazepam). Common drug interactions include cellulitis among females and blood creatinine increased among males.
The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Restoril. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Clarithromycin?
Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.
What is Restoril?
Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.
39 people who take Clarithromycin and Restoril together, and have interactions are studied.

What are the common drug interactions of Clarithromycin and Restoril, by gender? *:
female:
- Cellulitis (infection under the skin)
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chills (felling of cold)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Colitis ulcerative (inflammation of colon with ulcer)
- Crystal urine present
- Culture urine positive
- Decreased appetite
- Dental caries
male:
- Blood creatinine increased
- Renal impairment (severely reduced kidney function)
- Emotional distress
- Helicobacter gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium)
- Joint injury
- Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Aphagia (inability or refusal to swallow)
What are the common drug interactions of Clarithromycin and Restoril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Blood potassium decreased
- Coagulopathy (blood's ability to clot is impaired)
- Cough
- Malaise (a feeling of general discomfort or uneasiness)
- Respiratory tract congestion (blockage on respiratory system)
40-49:
- Dysuria (painful or difficult urination)
- Abdominal discomfort
- Abdominal distension
- Abdominal pain
- Anaemia (lack of blood)
- Anxiety
- Aspartate aminotransferase increased
- Breast cancer
- Chest discomfort
- Chest pain
50-59:
- Cardiac disorder
- Chronic kidney disease
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Diabetes mellitus inadequate control
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dysarthria (speech disorder)
- Dystonia (abnormal muscle tone)
- Emotional distress
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Endocarditis (inflammation in heart muscle)
60+:
- Chronic kidney disease
- Anaemia (lack of blood)
- Weight decreased
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Anxiety
- Aphagia (inability or refusal to swallow)
- Arthralgia (joint pain)
- Bacteraemia (presence of bacteria in the blood)
- Blood calcium decreased
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 33.33%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 30.77%
- Urinary Tract Infection: 6 people, 15.38%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.82%
- High Blood Pressure: 5 people, 12.82%
- Immunodeficiency Common Variable: 5 people, 12.82%
- Seasonal Allergy (allergic condition due to certain season): 4 people, 10.26%
- Infection: 4 people, 10.26%
- Constipation: 4 people, 10.26%
- Pain: 4 people, 10.26%
* Approximation only. Some reports may have incomplete information.
Do you take Clarithromycin and Restoril?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clarithromycin (45,044 reports)
- Restoril (13,522 reports)
Browse all drug interactions of Clarithromycin and Restoril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clarithromycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Restoril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clarithromycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restoril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on clarithromycin and temazepam (the active ingredients of Clarithromycin and Restoril, respectively), and Clarithromycin and Restoril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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