Clarithromycin and Zaroxolyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Zaroxolyn (metolazone). Common drug interactions include anaemia among females and lichenoid keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Zaroxolyn. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Zaroxolyn?

Zaroxolyn has active ingredients of metolazone. It is often used in high blood pressure. eHealthMe is studying from 5,244 Zaroxolyn users. Check the latest studies of Zaroxolyn.

On Jul, 20, 2026

12 people who take Clarithromycin and Zaroxolyn together, and have interactions are studied.

Clarithromycin and Zaroxolyn drug interactions.

What are the common drug interactions of Clarithromycin and Zaroxolyn, by gender? *:

female:

Anaemia (lack of blood)
Coagulopathy (blood's ability to clot is impaired)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Nikolsky's sign
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Diarrhoea
Digoxin toxicity
Dysarthria (speech disorder)
Fatigue (feeling of tiredness)
Heart rate decreased
Hypotension (abnormally low blood pressure)
Renal disorder (kidney disease)

What are the common drug interactions of Clarithromycin and Zaroxolyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Renal failure (kidney dysfunction)
Fatigue (feeling of tiredness)
Renal disorder (kidney disease)
Spinal osteoarthritis (joint cartilage loss in spine)

40-49:

n/a

50-59:

n/a

60+:

Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Nikolsky's sign
Syncope (loss of consciousness with an inability to maintain postural tone)
Skin oedema (swelling of skin)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Diarrhoea
Digoxin toxicity
Dysarthria (speech disorder)
Fluid retention (an abnormal accumulation of fluid in the blood)

What are the existing conditions these people have? *

Erysipelas (bacterial skin infection): 6 people, 50.00%
Hiv Infection: 2 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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