Claritin-d and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin-d (loratadine; pseudoephedrine sulfate) and Actonel (risedronate sodium). Common drug interactions include drug ineffective among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin-d and Actonel. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin-d?

Claritin-d has active ingredients of loratadine; pseudoephedrine sulfate. It is often used in allergies. eHealthMe is studying from 7,055 Claritin-d users. Check the latest studies of Claritin-d.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.



On Jul, 27, 2026

13 people who take Claritin-d and Actonel together, and have interactions are studied.

Claritin-d and Actonel drug interactions.

What are the common drug interactions of Claritin-D and Actonel, by gender? *:

female:

  1. Drug ineffective
  2. Pain
  3. Femur fracture
  4. Fracture displacement
  5. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  6. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  7. Drug intolerance (drug sensitivity)
  8. Skeletal injury (bone and supporting muscle injury)
  9. Arthralgia (joint pain)
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Anaemia (lack of blood)
  2. Pneumonia bacterial (pneumonia associated with bacterial infection)
  3. Haematoma (collection of blood outside the blood vessels)
  4. Muscular weakness (muscle weakness)
  5. Pain in extremity
  6. Pathological fracture (broken bone caused by disease)
  7. Post procedural haematoma (post procedural clotting of blood)
  8. Trendelenburg's symptom (the body is not able to maintain the centre of gravity on the side of the stance leg)
  9. Aphasia (damage to the parts of the brain that control language)
  10. Chest discomfort

What are the common drug interactions of Claritin-D and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthralgia (joint pain)
  2. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  3. Fall
  4. Femur fracture
  5. Fracture displacement
  6. Gait disturbance
  7. Groin pain
  8. Haematoma (collection of blood outside the blood vessels)
  9. Muscular weakness (muscle weakness)
  10. Pain in extremity

40-49:

  1. Accident
  2. Anger
  3. Arthralgia (joint pain)
  4. Back pain
  5. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Femur fracture
  8. Haematoma (collection of blood outside the blood vessels)
  9. Herpes zoster
  10. Homicidal ideation (thoughts about human killing another human)

50-59:

  1. Arthralgia (joint pain)
  2. Drug ineffective
  3. Pain
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Abdominal abscess (collection of pus in abdomen)
  6. Abscess (pus)
  7. Ankle fracture
  8. Bone disorder
  9. Cellulitis (infection under the skin)
  10. Chondropathy (disease of the cartilage)

60+:

  1. Anaemia (lack of blood)
  2. Pneumonia bacterial (pneumonia associated with bacterial infection)
  3. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
  4. Dyspnoea (difficult or laboured respiration)
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Dizziness
  7. Hyperhidrosis (abnormally increased sweating)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Vision blurred
  10. Asthma

What are the existing conditions these people have? *

  1. Quit Smoking: 5 people, 38.46%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 38.46%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 38.46%
  4. Seasonal Allergy (allergic condition due to certain season): 4 people, 30.77%
  5. High Blood Pressure: 2 people, 15.38%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 15.38%
  7. Hypersensitivity: 2 people, 15.38%
  8. Sneezing: 2 people, 15.38%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
  10. Eye Pruritus (eye itching): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin-d and Actonel?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Claritin-d and Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Claritin-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Claritin-d and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actonel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on loratadine; pseudoephedrine sulfate and risedronate sodium (the active ingredients of Claritin-d and Actonel, respectively), and Claritin-d and Actonel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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