Claritin-d and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin-d (loratadine; pseudoephedrine sulfate) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include pneumonia among females and sinusitis among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin-d and Hydramine. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin-d?

Claritin-d has active ingredients of loratadine; pseudoephedrine sulfate. It is often used in allergies. eHealthMe is studying from 7,055 Claritin-d users. Check the latest studies of Claritin-d.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

On Jul, 19, 2026

47 people who take Claritin-d and Hydramine together, and have interactions are studied.

Claritin-d and Hydramine drug interactions.

What are the common drug interactions of Claritin-D and Hydramine, by gender? *:

female:

Pneumonia
Fatigue (feeling of tiredness)
Abdominal discomfort
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Pain in extremity
Seasonal allergy (allergic condition due to certain season)
Back disorder
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Rash

male:

Sinusitis (inflammation of sinus)
Abdominal pain upper
Diarrhoea
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Red blood cell count increased

What are the common drug interactions of Claritin-D and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Palpitations (feelings or sensations that your heart is pounding or racing)
Respiratory rate increased (excess breathing rate/min)
Restlessness (not able to rest)

30-39:

n/a

40-49:

Blood pressure decreased
Chills (felling of cold)
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Sensation of foreign body
Skin warm

50-59:

Cellulitis (infection under the skin)
Sinusitis (inflammation of sinus)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Lower respiratory tract infection
Oedema peripheral (superficial swelling)
Abdominal hernia
Abnormal loss of weight
Abnormal weight gain
Allergy to plants
Asthenia (weakness)
Back pain
Bacteraemia (presence of bacteria in the blood)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 15 people, 31.91%
Asthma: 6 people, 12.77%
Immune System Disorder: 4 people, 8.51%
White Blood Cell Disorder: 3 people, 6.38%
Migraine (headache): 3 people, 6.38%
Hypersensitivity: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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