Claritin and Cryselle drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Cryselle (ethinyl estradiol; norgestrel). Common drug interactions include sleep apnoea syndrome among females.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Cryselle. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

What is Cryselle?

Cryselle has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 673 Cryselle users. Check the latest studies of Cryselle.



On Jul, 12, 2026

26 people who take Claritin and Cryselle together, and have interactions are studied.

Claritin and Cryselle drug interactions.

What are the common drug interactions of Claritin and Cryselle, by gender? *:

female:

  1. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  2. Depressed mood
  3. Nonalcoholic fatty liver disease
  4. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  5. Chronic kidney disease
  6. Colonoscopy
  7. Dehydration (dryness resulting from the removal of water)
  8. Depression
  9. Dizziness
  10. Hypertension (high blood pressure)

male:

n/a

What are the common drug interactions of Claritin and Cryselle, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Nausea (feeling of having an urge to vomit)

30-39:

  1. Diarrhoea
  2. Alanine aminotransferase increased
  3. Dehydration (dryness resulting from the removal of water)
  4. Nausea (feeling of having an urge to vomit)
  5. Urinary tract infection
  6. Alopecia (absence of hair from areas of the body)
  7. Arthralgia (joint pain)
  8. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  9. Depressed mood
  10. Dizziness

40-49:

  1. Headache (pain in head)
  2. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  3. Palpitations (feelings or sensations that your heart is pounding or racing)
  4. Renal failure (kidney dysfunction)
  5. Chronic kidney disease
  6. Colonoscopy
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Weight increased
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Dizziness

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 50.00%
  2. Headache (pain in head): 5 people, 19.23%
  3. Acne (skin problems that cause pimples): 4 people, 15.38%
  4. Hypersensitivity: 4 people, 15.38%
  5. Stress And Anxiety: 4 people, 15.38%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
  7. Pain: 4 people, 15.38%
  8. Multiple Allergies (allergy to multiple agents): 4 people, 15.38%
  9. Cough: 3 people, 11.54%
  10. Depression: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and Cryselle?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Claritin and Cryselle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cryselle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Claritin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cryselle and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loratadine and ethinyl estradiol; norgestrel (the active ingredients of Claritin and Cryselle, respectively), and Claritin and Cryselle (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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