Claritin and Estraderm drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Claritin (loratadine) and Estraderm (estradiol). Common drug interactions include chest pain among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Claritin and Estraderm. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.
What is Claritin?
Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.
What is Estraderm?
Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.
46 people who take Claritin and Estraderm together, and have interactions are studied.

What are the common drug interactions of Claritin and Estraderm, by gender? *:
female:
- Chest pain
- Pain
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
- Osteoporosis (bones weak and more likely to break)
- Breast cancer
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Diarrhoea
- Pain in extremity
- Rash
- Cough
male:
- Fall
- Abdominal pain upper
- Blood urea nitrogen/creatinine ratio increased
- Bronchopleural fistula
- Bunion (a painful swelling on the first joint of the big toe)
- Cancer pain
- Cardiomegaly (increased size of heart than normal)
- Cerebrovascular disorder (disease of brain)
- Cervical spinal stenosis (narrowing of the spinal canal in the neck)
- Chest pain
What are the common drug interactions of Claritin and Estraderm, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain
- Aggression
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Constipation
- Crying
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Depressed mood
- Diarrhoea
- Disturbance in attention
- Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
40-49:
- Arthralgia (joint pain)
- Breast cancer
- Breast necrosis (death of cells or tissues through injury or disease in beast)
- Dyspnoea (difficult or laboured respiration)
- Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Nasal septum deviation (deviated nasal septum)
- Osteoporosis (bones weak and more likely to break)
- Pelvic pain
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
50-59:
- Injury
- Nausea (feeling of having an urge to vomit)
- Renal failure acute (rapid kidney dysfunction)
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
- Wheezing (a high-pitched whistling sound made while you breath)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Blood urea nitrogen/creatinine ratio increased
60+:
- Spinal osteoarthritis (joint cartilage loss in spine)
- Abdominal pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Dyspnoea (difficult or laboured respiration)
- Endometrial atrophy
- Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
- Granuloma (a small area of inflammation due to tissue injury)
- Lymphoedema (localized fluid retention and tissue swelling)
- Osteoporosis (bones weak and more likely to break)
- Pain in extremity
What are the existing conditions these people have? *
- Menopause (end of monthly cycles in women): 13 people, 28.26%
- Osteoporosis (bones weak and more likely to break): 11 people, 23.91%
- Menopausal Symptoms: 8 people, 17.39%
- Bone Density Abnormal: 8 people, 17.39%
- Seasonal Allergy (allergic condition due to certain season): 6 people, 13.04%
- Hypersensitivity: 6 people, 13.04%
- Depression: 5 people, 10.87%
- High Blood Cholesterol: 4 people, 8.70%
- Vaginal Infection: 3 people, 6.52%
- Sinusitis (inflammation of sinus): 3 people, 6.52%
* Approximation only. Some reports may have incomplete information.
Do you take Claritin and Estraderm?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Claritin and Estraderm:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Claritin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Estraderm:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Claritin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Estraderm and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on loratadine and estradiol (the active ingredients of Claritin and Estraderm, respectively), and Claritin and Estraderm (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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