Claritin and Ibrutinib drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Ibrutinib (ibrutinib). Common drug interactions include nail ridging among females and encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Ibrutinib. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,316 Claritin users. Check the latest studies of Claritin.

What is Ibrutinib?

Ibrutinib has active ingredients of ibrutinib. eHealthMe is studying from 13,529 Ibrutinib users. Check the latest studies of Ibrutinib.

On Aug, 06, 2026

35 people who take Claritin and Ibrutinib together, and have interactions are studied.

Claritin and Ibrutinib drug interactions.

What are the common drug interactions of Claritin and Ibrutinib, by gender? *:

female:

Nail ridging (nail has raised ridges and is thin and curved inward)
Night sweats (sweating in night)
Onychoclasis (breaking of the nails)
Otitis externa (external ear infection)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Red blood cell count decreased
Reticulocyte count decreased
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Urge incontinence (urinary incontinence)
Varicose vein (veins that have become enlarged and tortuous)

male:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypotension (abnormally low blood pressure)
Abdominal discomfort
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain
Adverse drug reaction
Agitation (state of anxiety or nervous excitement)
Amylase increased
Asthenia (weakness)
Blood alkaline phosphatase increased

What are the common drug interactions of Claritin and Ibrutinib, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cough
Erythema (redness of the skin)
Erythema of eyelid (redness of the eyelid)
Eye pruritus (eye itching)
Fatigue (feeling of tiredness)
Gastric infection (infection of stomach)
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Insomnia (sleeplessness)

50-59:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Hypokalaemia (low potassium)
Vomiting
Overdose
Ear pain
Headache (pain in head)
Multi-organ failure (multisystem organ failure)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Haemoglobin decreased
Oedema peripheral (superficial swelling)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Frequent bowel movements
Hypotension (abnormally low blood pressure)
Metastases to meninges (cancer spreads to meninges)
Nausea (feeling of having an urge to vomit)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 15 people, 42.86%
Nausea (feeling of having an urge to vomit): 11 people, 31.43%
Depression: 8 people, 22.86%
Seasonal Allergy (allergic condition due to certain season): 8 people, 22.86%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 8 people, 22.86%
Hypersensitivity: 7 people, 20.00%
Burkitt Lymphoma (cancer of the lymphatic system): 6 people, 17.14%
Nausea And Vomiting: 5 people, 14.29%
Constipation: 5 people, 14.29%
Pain: 5 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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