Claritin and Pentam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Pentam (pentamidine isethionate). Common drug interactions include hypomagnesaemia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Pentam. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

What is Pentam?

Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.

On Jul, 13, 2026

54 people who take Claritin and Pentam together, and have interactions are studied.

What are the common drug interactions of Claritin and Pentam, by gender? *:

female:

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Impaired healing
Metastases to liver (cancer spreads to liver)
Mucosal inflammation (infection of mucous membrane)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pyrexia (fever)
Swelling face
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Arthralgia (joint pain)
Cataract (clouding of the lens inside the eye)

male:

Pyrexia (fever)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Malignant neoplasm progression (cancer tumour came back)
Pain
Arthralgia (joint pain)
Blood bilirubin increased
Blood lactate dehydrogenase increased
Bone density decreased
Delirium (wild excitement)
Diarrhoea

What are the common drug interactions of Claritin and Pentam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Neutropenia (an abnormally low number of neutrophils)

10-19:

n/a

20-29:

Anaphylactic reaction (serious allergic reaction)
Diarrhoea
Mucosal inflammation (infection of mucous membrane)
Pyrexia (fever)
Rash
Staphylococcal bacteraemia (a bacterial infection of blood)
Staphylococcal infection (an infection with staphylococcus bacteria)
Vomiting
Hypersensitivity

30-39:

Anisocytosis (patient's red blood cells are of unequal size)
Blood bilirubin increased
Blood lactate dehydrogenase increased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Haptoglobin decreased
Infection
Injection site cellulitis (injection site inflammation)
Injection site extravasation (flow of (blood or lymph) from injection site)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

40-49:

Acinetobacter bacteraemia (infection of bacteria)
Anaemia (lack of blood)
Blood albumin decreased
Blood alkaline phosphatase increased
Blood calcium decreased
Blood lactate dehydrogenase increased
Blood potassium decreased
Blood pressure decreased
Blood urea increased
Bone marrow failure

50-59:

Frequent bowel movements
Gastritis (inflammation of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematocrit decreased
Hand fracture
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)

60+:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pyrexia (fever)
Colitis (inflammation of colon)
Dyspnoea exertional (breathlessness or shortness of breath)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal toxicity (damage to digestive tract by any substance)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 18.52%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 11.11%
High Blood Pressure: 6 people, 11.11%
Muscle Spasms (muscle contraction): 5 people, 9.26%
Allergic Rhinitis: 4 people, 7.41%
Bone Marrow Conditioning Regimen: 4 people, 7.41%
Dry Eyes (lack of adequate tears): 4 people, 7.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 7.41%
Multiple Myeloma (cancer of the plasma cells): 4 people, 7.41%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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