Claritin and Robinul drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Robinul (glycopyrrolate). Common drug interactions include syncope among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Robinul. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,316 Claritin users. Check the latest studies of Claritin.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

53 people who take Claritin and Robinul together, and have interactions are studied.

What are the common drug interactions of Claritin and Robinul, by gender? *:

female:

Syncope (loss of consciousness with an inability to maintain postural tone)
Atrophic vulvovaginitis (inflammation of the vulva)
Carotid artery disease
Carotid artery occlusion (artery blockage)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Cough
Deafness
Depression
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

male:

Chronic kidney disease
Emotional distress
Gait disturbance
Groin abscess (pus in groin)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Tooth abscess (pus formation in tooth)
Urinary tract infection
Abscess (pus)
Ankle fracture

What are the common drug interactions of Claritin and Robinul, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Pancreatitis (inflammation of pancreas)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Atelectasis (partial or complete collapse of the lung)
Bacterial tracheitis (bacterial infection of the trachea)
Bradycardia (abnormally slow heart action)
Death
Diarrhoea
Haematemesis (vomiting of blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)

10-19:

Bacteraemia (presence of bacteria in the blood)
Calculus urinary (stone in urinary system)
Crystalluria present
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
External ear cellulitis (outer ear skin infection)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Oliguria (not enough urine)
Renal colic (renal pain)
Renal failure (kidney dysfunction)
Tracheitis (an inflammation of the trachea)

20-29:

Pain
Pyrexia (fever)
Abdominal pain lower
Abdominal pain upper
Back pain
Biliary colic
Gallbladder disorder
Nausea (feeling of having an urge to vomit)
Pancreatitis chronic (chronic inflammation of pancreas)
Vomiting

30-39:

Arthralgia (joint pain)
Back pain
Infusion related reaction
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Pain in jaw

40-49:

Infection
Iron deficiency anaemia
Joint range of motion decreased (disease of joint movement)
Malaise (a feeling of general discomfort or uneasiness)
Myopia (difficult to see objects that are far away)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Neck pain
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

50-59:

Abdominal pain upper
Abdominal distension
Abdominal pain
Adrenal mass
Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Back pain
Chest pain
Deafness unilateral

60+:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Dizziness
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Groin pain
Hospitalisation
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the existing conditions these people have? *

Pain: 11 people, 20.75%
Nausea (feeling of having an urge to vomit): 8 people, 15.09%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 13.21%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 11.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 11.32%
Hypersensitivity: 5 people, 9.43%
Hiv Infection: 4 people, 7.55%
Cough: 4 people, 7.55%
Muscle Spasms (muscle contraction): 4 people, 7.55%
Muscle Aches (muscle pain): 4 people, 7.55%

* Approximation only. Some reports may have incomplete information.

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