Claritin and Zonisamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Zonisamide (zonisamide). Common drug interactions include erythema among females and rhinovirus infection among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Zonisamide. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

On Jul, 13, 2026

60 people who take Claritin and Zonisamide together, and have interactions are studied.

Claritin and Zonisamide drug interactions.

What are the common drug interactions of Claritin and Zonisamide, by gender? *:

female:

Erythema (redness of the skin)
Exostosis (formation of new bone on the surface of a bone)
Exposed bone in jaw
Facial bones fracture (bone fracture of face)
Febrile neutropenia (fever with reduced white blood cells)
Feeling hot
Foot fracture
Gait disturbance
Dizziness
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

male:

Rhinovirus infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Fatigue (feeling of tiredness)
Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Intestinal prolapse
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Photophobia (extreme sensitivity to light)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Therapeutic response decreased (less preventive response)

What are the common drug interactions of Claritin and Zonisamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pancreatitis (inflammation of pancreas)
Diarrhoea
Haematemesis (vomiting of blood)
Muscle spasms (muscle contraction)
Pain
Pyrexia (fever)
Vomiting

10-19:

Somnolence (a state of near-sleep, a strong desire for sleep)
Aggression
Crying
Decreased appetite
Ear infection
Fatigue (feeling of tiredness)
Rhinovirus infection
Bradycardia (abnormally slow heart action)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nocturia (the need to get up in the night to urinate)

20-29:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Dizziness
Drug intolerance (drug sensitivity)
Endocrine disorder (endocrine diseases are disorders of the endocrine system)
Fall
Periorbital haemorrhage (bleeding around the eyes)
Visual impairment
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Somnambulism (sleep walking)

30-39:

Acidosis (build-up of carbon dioxide in the blood)
Asthma
Blindness transient (sudden loss of vision)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cough
Delayed recovery from anaesthesia
Injury
Osteonecrosis (death of bone)

40-49:

Periorbital haemorrhage (bleeding around the eyes)
Rash macular (small, flat red spots)
Urticaria (rash of round, red welts on the skin that itch intensely)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Breast cancer stage ii
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Endocrine disorder (endocrine diseases are disorders of the endocrine system)
Hepatitis (inflammation of the liver)
Impaired healing
Lethargy (tiredness)

50-59:

Injection site pain
Suicide attempt
Back pain
Blindness
Blood creatinine increased
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone loss
Bone pain
Bone swelling
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 15.00%
Migraine (headache): 5 people, 8.33%
Immunodeficiency Common Variable: 5 people, 8.33%
Asthma: 5 people, 8.33%
Hypersensitivity: 4 people, 6.67%
Drowsiness: 4 people, 6.67%
Depression: 4 people, 6.67%
Stress And Anxiety: 3 people, 5.00%
Constipation: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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