Cleocin and Chlorhexidine gluconate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cleocin (clindamycin phosphate) and Chlorhexidine gluconate (chlorhexidine gluconate). Common drug interactions include osteonecrosis of jaw among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Cleocin and Chlorhexidine gluconate. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

On Jul, 20, 2026

76 people who take Cleocin and Chlorhexidine gluconate together, and have interactions are studied.

Cleocin and Chlorhexidine gluconate drug interactions.

What are the common drug interactions of Cleocin and Chlorhexidine Gluconate, by gender? *:

female:

Osteonecrosis of jaw (death of bone of jaw)
Hypertension (high blood pressure)
Diarrhoea
Hypoaesthesia (reduced sense of touch or sensation)
Osteopenia (a condition where bone mineral density is lower than normal)
Toothache (tooth pain)
Gait disturbance
Neuropathy peripheral (surface nerve damage)
Onychomycosis (fungal infection of the nail)
Constipation

male:

Anaemia (lack of blood)
Anxiety
Pneumonia
Pyrexia (fever)
Back pain
Dizziness
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)

What are the common drug interactions of Cleocin and Chlorhexidine Gluconate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Anxiety
Arthralgia (joint pain)
Deformity (disfigurement)
Diarrhoea
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional distress
Gait disturbance
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Osteonecrosis of jaw (death of bone of jaw)
Pain
Pyrexia (fever)
Arthralgia (joint pain)
Insomnia (sleeplessness)
Osteomyelitis (infection of bone)
Anaemia (lack of blood)
Back pain
Decreased interest
Diarrhoea

60+:

Anxiety
Arthralgia (joint pain)
Osteopenia (a condition where bone mineral density is lower than normal)
Anaemia (lack of blood)
Decreased interest
General physical health deterioration (weak health status)
Pain in jaw
Pneumonia
Dental caries
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 29 people, 38.16%
Neoplasm Malignant (cancer tumour): 12 people, 15.79%
Stress And Anxiety: 8 people, 10.53%
Pain: 7 people, 9.21%
Nausea (feeling of having an urge to vomit): 7 people, 9.21%
Stomatitis (inflammation of mucous membrane of mouth): 5 people, 6.58%
Small Intestine Carcinoma Metastatic (cancer tumour of small intestine spreads to other part): 5 people, 6.58%
Rashes (redness): 5 people, 6.58%
Nausea And Vomiting: 5 people, 6.58%
Diarrhea: 5 people, 6.58%

* Approximation only. Some reports may have incomplete information.

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