Cleocin and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cleocin (clindamycin phosphate) and Cyclophosphamide (cyclophosphamide). Common drug interactions include atrial fibrillation among females and aspartate aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Cleocin and Cyclophosphamide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.



On Jul, 16, 2026

17 people who take Cleocin and Cyclophosphamide together, and have interactions are studied.

Cleocin and Cyclophosphamide drug interactions.

What are the common drug interactions of Cleocin and Cyclophosphamide, by gender? *:

female:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Implant infection (infection at implant site)
  3. Alopecia (absence of hair from areas of the body)
  4. Alopecia totalis (loss of all head hair)
  5. Cellulitis (infection under the skin)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Hair colour changes
  9. Implant site reaction
  10. Injection site erythema (redness at injection site)

male:

  1. Aspartate aminotransferase increased
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Cardiac murmur (an heart sound in valve abnormality)
  5. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  6. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  7. Confusional state
  8. Decreased interest
  9. Dental caries
  10. Depression

What are the common drug interactions of Cleocin and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cellulitis (infection under the skin)
  2. Alopecia (absence of hair from areas of the body)
  3. Implant infection (infection at implant site)
  4. Injection site erythema (redness at injection site)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Psychological trauma
  7. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

50-59:

  1. Alopecia totalis (loss of all head hair)
  2. Diarrhoea
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Hair colour changes
  5. Nausea (feeling of having an urge to vomit)
  6. Oropharyngeal pain
  7. Vomiting
  8. Alanine aminotransferase increased
  9. Aspartate aminotransferase increased
  10. Chronic eosinophilic leukaemia (long lasting form of blood cell cancer)

60+:

  1. Haematuria (presence of blood in urine)
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Bone loss
  4. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  5. Cardiac murmur (an heart sound in valve abnormality)
  6. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  7. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  8. Confusional state
  9. Decreased interest
  10. Dental caries

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 5 people, 29.41%
  2. Nausea And Vomiting: 4 people, 23.53%
  3. Pain: 3 people, 17.65%
  4. Chronic Lymphocytic Leukaemia Recurrent (repeated cancer of blood cells known as lymphocytes): 3 people, 17.65%
  5. Itching: 2 people, 11.76%
  6. Eczema Herpeticum (feverish condition and widespread eruption of vesicles): 2 people, 11.76%
  7. Headache (pain in head): 2 people, 11.76%
  8. Vulval Disorder: 1 person, 5.88%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 1 person, 5.88%
  10. Breast Cancer: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cleocin and Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cleocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cleocin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clindamycin phosphate and cyclophosphamide (the active ingredients of Cleocin and Cyclophosphamide, respectively), and Cleocin and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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