Clexane and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clexane (enoxaparin sodium) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include cerebellar haemorrhage among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Clexane and Centrum. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,681 Centrum users. Check the latest studies of Centrum.



On Oct, 14, 2025

19 people who take Clexane and Centrum together, and have interactions are studied.

Clexane and Centrum drug interactions.

What are the common drug interactions of Clexane and Centrum, by gender? *:

female:

  1. Cerebellar haemorrhage (bleeding in cerebeller)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Hydrocephalus (water on the brain)
  4. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  5. Body temperature decreased
  6. Burning sensation
  7. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Dermatitis allergic (inflammation of the skin due allergic reaction)
  10. Fall

male:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Anaemia (lack of blood)
  3. Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
  4. Haemoglobin decreased
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Haemorrhage (bleeding)
  7. Platelet count decreased
  8. Respiratory tract infection bacterial
  9. Splenomegaly (enlargement of spleen)
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

What are the common drug interactions of Clexane and Centrum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Foetal death (death of foetus)

40-49:

  1. Cerebellar haemorrhage (bleeding in cerebeller)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Hydrocephalus (water on the brain)
  4. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  5. Pleural effusion (water on the lungs)

50-59:

n/a

60+:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Anaemia (lack of blood)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Constipation
  5. Dermatitis allergic (inflammation of the skin due allergic reaction)
  6. Disease complication
  7. Drug ineffective
  8. Fall
  9. Femur fracture
  10. Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 26.32%
  2. Multiple Myeloma (cancer of the plasma cells): 5 people, 26.32%
  3. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 15.79%
  4. Diabetes: 3 people, 15.79%
  5. Pvt: 2 people, 10.53%
  6. Osteoporosis (bones weak and more likely to break): 2 people, 10.53%
  7. Iron Deficiency Anaemia: 2 people, 10.53%
  8. Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 2 people, 10.53%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.53%
  10. Hepatitis C: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Clexane and Centrum?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clexane and Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clexane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enoxaparin sodium and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Clexane and Centrum, respectively), and Clexane and Centrum (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: