Clexane and Dipyrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clexane (enoxaparin sodium) and Dipyrone (metamizole). Common drug interactions include arthralgia among females and mucosal inflammation among males.

The phase IV clinical study analyzes what interactions people have when they take Clexane and Dipyrone. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

What is Dipyrone?

Dipyrone has active ingredients of metamizole. eHealthMe is studying from 1,876 Dipyrone users. Check the latest studies of Dipyrone.



On Jul, 09, 2026

13 people who take Clexane and Dipyrone together, and have interactions are studied.

Clexane and Dipyrone drug interactions.

What are the common drug interactions of Clexane and Dipyrone, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Myalgia (muscle pain)
  3. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  4. Pain
  5. Constipation
  6. Depression
  7. Fall
  8. Gastrointestinal infection (infection of stomach and intestine)
  9. Hot flush (sudden feelings of heat)
  10. Humerus fracture (injury to the upper arm bone)

male:

  1. Mucosal inflammation (infection of mucous membrane)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Depressed level of consciousness
  5. Echolalia (meaningless repetition of another person's spoken words -psychiatric disorder)
  6. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  7. Hypertension (high blood pressure)
  8. Irritability
  9. Nystagmus (a condition of involuntary eye movement)
  10. Partial seizures (seizures which affect only a part of the brain at onset)

What are the common drug interactions of Clexane and Dipyrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abdominal pain
  2. Agitation (state of anxiety or nervous excitement)
  3. Amaurosis (partial or total blindness without visible change in the eye)
  4. Aphasia (damage to the parts of the brain that control language)
  5. Ataxia (loss of full control of bodily movements)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Depressed level of consciousness
  8. Echolalia (meaningless repetition of another person's spoken words -psychiatric disorder)
  9. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  10. Hypertension (high blood pressure)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  3. Arthralgia (joint pain)
  4. Cardiac disorder
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Diabetes mellitus inadequate control
  7. Diarrhoea
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Hypertension (high blood pressure)
  10. Myalgia (muscle pain)

60+:

  1. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  2. Mucosal inflammation (infection of mucous membrane)
  3. Pruritus (severe itching of the skin)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Rash generalised (rash on most of body parts)
  6. Renal impairment (severely reduced kidney function)
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Vision blurred
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

  1. Pain: 4 people, 30.77%
  2. High Blood Pressure: 3 people, 23.08%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 23.08%
  4. Urination - Excessive Volume: 2 people, 15.38%
  5. Lung Disorder (lung disease): 2 people, 15.38%
  6. Breathing Sounds - Abnormal (Stridor): 2 people, 15.38%
  7. Cardiovascular Insufficiency (inadequate functioning of heart): 2 people, 15.38%
  8. Constipation: 2 people, 15.38%
  9. Diarrhea: 2 people, 15.38%
  10. Hyperglycemia (high blood sugar): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Clexane and Dipyrone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clexane and Dipyrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clexane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dipyrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clexane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dipyrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enoxaparin sodium and metamizole (the active ingredients of Clexane and Dipyrone, respectively), and Clexane and Dipyrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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