Clexane and Olanzapine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clexane (enoxaparin sodium) and Olanzapine (olanzapine). Common drug interactions include blood alkaline phosphatase increased among females and dysphagia among males.
The phase IV clinical study analyzes what interactions people have when they take Clexane and Olanzapine. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.
What is Clexane?
Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.
What is Olanzapine?
Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.
89 people who take Clexane and Olanzapine together, and have interactions are studied.

What are the common drug interactions of Clexane and Olanzapine, by gender? *:
female:
- Blood alkaline phosphatase increased
- Gamma-glutamyltransferase increased
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pulmonary embolism (blockage of the main artery of the lung)
- Pyrexia (fever)
- Sudden death
- Thrombocytopenia (decrease of platelets in blood)
- Transaminases increased
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bradycardia (abnormally slow heart action)
male:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Self-injurious ideation
- Tension (the act or process of stretching something tight)
- Acute respiratory failure
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Psychotic disorder
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Drooling (drop saliva uncontrollably from the mouth)
- Hemiparesis (weakness on one side of the body)
What are the common drug interactions of Clexane and Olanzapine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
30-39:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Salivary hypersecretion (excess saliva secretion)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Aggression
- Delusion (a false belief or opinion)
- Duodenitis (inflammation of the duodenum)
- Gastritis (inflammation of stomach)
- Hyporeflexia (a condition of below normal or absent reflexes)
- Pleural effusion (water on the lungs)
40-49:
- Dehydration (dryness resulting from the removal of water)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Osteonecrosis (death of bone)
- Intentional self-injury
- Pulmonary embolism (blockage of the main artery of the lung)
- Sopor (sleep)
50-59:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
- Suicidal ideation
- Therapeutic response decreased (less preventive response)
- Pyrexia (fever)
- Sudden death
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fall
- Femoral neck fracture (neck of femur bone fracture)
- Leukopenia (less number of white blood cells in blood)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Overdose
- Pulmonary oedema (fluid accumulation in the lungs)
- Drug level above therapeutic
What are the existing conditions these people have? *
- Pain: 9 people, 10.11%
- High Blood Pressure: 9 people, 10.11%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 8.99%
- Psychotic Disorder: 7 people, 7.87%
- Nausea (feeling of having an urge to vomit): 7 people, 7.87%
- Depression: 7 people, 7.87%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 7 people, 7.87%
- Insomnia (sleeplessness): 5 people, 5.62%
* Approximation only. Some reports may have incomplete information.
Do you take Clexane and Olanzapine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clexane (14,679 reports)
- Olanzapine (69,242 reports)
Browse all drug interactions of Clexane and Olanzapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clexane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Olanzapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clexane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Olanzapine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on enoxaparin sodium and olanzapine (the active ingredients of Clexane and Olanzapine, respectively), and Clexane and Olanzapine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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