Clexane and Xeloda drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clexane (enoxaparin sodium) and Xeloda (capecitabine). Common drug interactions include nausea among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Clexane and Xeloda. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

What is Xeloda?

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. eHealthMe is studying from 46,649 Xeloda users. Check the latest studies of Xeloda.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

53 people who take Clexane and Xeloda together, and have interactions are studied.

What are the common drug interactions of Clexane and Xeloda, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Necrosis (the death of body tissue)
Nystagmus (a condition of involuntary eye movement)
Tremor (trembling or shaking movements in one or more parts of your body)
Constipation
Disease progression
Hyperglycaemia (high blood sugar)
Hypertensive crisis
Liver disorder (liver diseases)
Proteinuria (presence of protein in the urine)

male:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Pneumonia
Abdominal pain
Cystitis haemorrhagic (blood in the urine and painful voiding)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
Haematuria (presence of blood in urine)
Hypokalaemia (low potassium)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Clexane and Xeloda, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Hypophagia (reduced food intake)
Impaired healing
Liver injury
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myopathy (a muscular disease in which the muscle fibres do not function)
Oral discomfort (pain or irritation in mouth)

50-59:

Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Oedema peripheral (superficial swelling)
Sensory disturbance (sense disturbance)
Swelling face
General physical health deterioration (weak health status)
Constipation
Hyperglycaemia (high blood sugar)
Hypertensive crisis
Stomatitis (inflammation of mucous membrane of mouth)
Thrombocytopenia (decrease of platelets in blood)

60+:

Hepatic failure (liver failure)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Diarrhoea
Dehydration (dryness resulting from the removal of water)
Neoplasm progression (growth of tumour)
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery stenosis (narrowing of coronary artery)
Drug resistance (reduction in effectiveness of a drug)

What are the existing conditions these people have? *

Pain: 18 people, 33.96%
Nausea (feeling of having an urge to vomit): 17 people, 32.08%
Nausea And Vomiting: 16 people, 30.19%
Diarrhea: 16 people, 30.19%
Urinary Tract Infection: 14 people, 26.42%
Blood Potassium Decreased: 14 people, 26.42%
Thrombosis (formation of a blood clot inside a blood vessel): 14 people, 26.42%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 12 people, 22.64%
Sepsis (a severe blood infection that can lead to organ failure and death): 11 people, 20.75%
High Blood Pressure: 7 people, 13.21%

* Approximation only. Some reports may have incomplete information.

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