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Climara and Acetazolamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Climara (estradiol) and Acetazolamide (acetazolamide). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Climara and Acetazolamide. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Climara?

Climara has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,706 Climara users. Check the latest studies of Climara.

What is Acetazolamide?

Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

11 people who take Climara and Acetazolamide together, and have interactions are studied.

Climara and Acetazolamide drug interactions.

What are the common drug interactions of Climara and Acetazolamide, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Oedema (fluid collection in tissue)
  3. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  4. Nephrolithiasis (calculi in the kidneys)
  5. Rhinorrhoea (watery mucus discharge from the nose)
  6. Single functional kidney (single kidney)
  7. Dyskinesia (abnormality or impairment of voluntary movement)
  8. Foot deformity (functional disability of foot)
  9. Hypersensitivity
  10. Neck pain

male:

n/a

What are the common drug interactions of Climara and Acetazolamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Foot deformity (functional disability of foot)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 100.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 72.73%
  3. Pain: 1 person, 9.09%
  4. Drowsiness: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Climara and Acetazolamide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Climara and Acetazolamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Climara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetazolamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Climara and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetazolamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on estradiol and acetazolamide (the active ingredients of Climara and Acetazolamide, respectively), and Climara and Acetazolamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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