Climara and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Climara (estradiol) and Morphine sulfate (morphine sulfate). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Climara and Morphine sulfate. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Climara?

Climara has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,706 Climara users. Check the latest studies of Climara.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

On Jul, 19, 2026

26 people who take Climara and Morphine sulfate together, and have interactions are studied.

Climara and Morphine sulfate drug interactions.

What are the common drug interactions of Climara and Morphine Sulfate, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Intervertebral disc protrusion (spinal disc protrusion)
Headache (pain in head)
Tricuspid valve incompetence (inefficient heart valve)
Vomiting
Aortic valve incompetence
Fibromyalgia (a long-term condition which causes pain all over the body)
Intestinal obstruction
Mitral valve incompetence (inefficient heart valve)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)

male:

n/a

What are the common drug interactions of Climara and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pyrexia (fever)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Myocarditis (inflammation of heart muscle myocardium)
Urinary tract infection
Uveitis (inflammation of the uvea)

50-59:

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Excoriation (to tear or wear off the skin of)
Fluid retention (an abnormal accumulation of fluid in the blood)
Foot fracture
Gastritis (inflammation of stomach)
Hyperhidrosis (abnormally increased sweating)
Hyperventilation
Impaired healing
Intervertebral disc degeneration (spinal disc degeneration)
Joint sprain (an injury to joint surrounding flexible fibres)

60+:

Decreased appetite
Dehydration (dryness resulting from the removal of water)
Neck pain
Pneumonia
Rhinorrhoea (watery mucus discharge from the nose)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Vomiting
Drug hypersensitivity
Headache (pain in head)
Hearing disability

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 19.23%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 19.23%
Stress And Anxiety: 2 people, 7.69%
Nausea (feeling of having an urge to vomit): 2 people, 7.69%
Chronic Fatigue Syndrome (disorder that causes extreme fatigue): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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