Climara and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Climara (estradiol) and Propulsid (cisapride monohydrate). Common drug interactions include electrocardiogram qt prolonged among females.

The phase IV clinical study analyzes what interactions people have when they take Climara and Propulsid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Climara?

Climara has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,706 Climara users. Check the latest studies of Climara.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

On Jul, 15, 2026

13 people who take Climara and Propulsid together, and have interactions are studied.

Climara and Propulsid drug interactions.

What are the common drug interactions of Climara and Propulsid, by gender? *:

female:

Electrocardiogram qt prolonged
Constipation
Blood bilirubin increased
Cardiac disorder
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal toxicity (damage to digestive tract by any substance)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Neoplasm malignant (cancer tumour)
Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)

male:

n/a

What are the common drug interactions of Climara and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Application site reaction
Infection
Injection site pain
Injection site reaction
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Urinary tract infection
Vaginitis (inflammation of the vagina)

50-59:

Blood bilirubin increased
Cardiac disorder
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal toxicity (damage to digestive tract by any substance)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Neoplasm malignant (cancer tumour)
Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)
Rash

60+:

Application site reaction
Arrhythmia (irregular heartbeat)
Chest pain
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Gastrointestinal Motility Disorder (abnormal intestinal contractions): 3 people, 23.08%
Nausea And Vomiting: 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 7.69%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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