Clindamycin phosphate and Lomotil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clindamycin phosphate (clindamycin phosphate) and Lomotil (atropine sulfate; diphenoxylate hydrochloride). Common drug interactions include nightmare among females and deafness among males.

The phase IV clinical study analyzes what interactions people have when they take Clindamycin phosphate and Lomotil. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

What is Lomotil?

Lomotil has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea. eHealthMe is studying from 19,184 Lomotil users. Check the latest studies of Lomotil.



On Apr, 27, 2026

23 people who take Clindamycin phosphate and Lomotil together, and have interactions are studied.

Clindamycin phosphate and Lomotil drug interactions.

What are the common drug interactions of Clindamycin Phosphate and Lomotil, by gender? *:

female:

  1. Nightmare (unpleasant dream)
  2. Ocular hyperaemia (an abnormally large amount of blood in eye)
  3. Onychalgia (nail biting)
  4. Onychoclasis (breaking of the nails)
  5. Onychomycosis (fungal infection of the nail)
  6. Oral mucosal blistering (mouth ulcer)
  7. Oropharyngeal pain
  8. Pain in extremity
  9. Poor quality sleep
  10. Rash papular (redness with papule)

male:

  1. Deafness
  2. Drug ineffective
  3. Erythema (redness of the skin)
  4. General physical health deterioration (weak health status)
  5. Haemorrhagic diathesis (bleeding tendency)
  6. Influenza
  7. Joint swelling
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Mouth ulceration (mouth ulcers)
  10. Muscle spasms (muscle contraction)

What are the common drug interactions of Clindamycin Phosphate and Lomotil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Bipolar disorder (mood disorder)
  3. Blood pressure decreased
  4. Headache (pain in head)
  5. Salmonellosis (an infection with salmonella bacteria)
  6. Self-injurious ideation
  7. Suicidal ideation
  8. Therapeutic response unexpected

50-59:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Constipation
  3. Cough
  4. Influenza
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Vomiting
  7. Abdominal pain
  8. Abdominal tenderness
  9. Alanine aminotransferase increased
  10. Aspartate aminotransferase increased

60+:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Rash
  3. Skin exfoliation (removal of the oldest dead skin cells)
  4. Stomatitis (inflammation of mucous membrane of mouth)
  5. Activated partial thromboplastin time prolonged
  6. Arthralgia (joint pain)
  7. Back pain
  8. Blood bilirubin increased
  9. Breast cancer
  10. Death

What are the existing conditions these people have? *

  1. Cervix Carcinoma (cancer of cervix): 3 people, 13.04%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.70%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
  4. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 8.70%
  5. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 8.70%
  6. K-Ras Gene Mutation: 2 people, 8.70%
  7. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 2 people, 8.70%
  8. Drowsiness: 2 people, 8.70%
  9. Colorectal Cancer Stage Iv (cancer of colon and rectal spreads to liver or lung): 2 people, 8.70%
  10. Colon Cancer: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Clindamycin phosphate and Lomotil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clindamycin phosphate and Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clindamycin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lomotil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clindamycin phosphate and atropine sulfate; diphenoxylate hydrochloride (the active ingredients of Clindamycin phosphate and Lomotil, respectively), and Clindamycin phosphate and Lomotil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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