Clindamycin phosphate and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clindamycin phosphate (clindamycin phosphate) and Phenergan (promethazine hydrochloride). Common drug interactions include depression among females and incisional hernia among males.

The phase IV clinical study analyzes what interactions people have when they take Clindamycin phosphate and Phenergan. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

11 people who take Clindamycin phosphate and Phenergan together, and have interactions are studied.

Clindamycin phosphate and Phenergan drug interactions.

What are the common drug interactions of Clindamycin Phosphate and Phenergan, by gender? *:

female:

Depression
Pain
Anxiety
Fatigue (feeling of tiredness)
Impaired healing
Influenza like illness
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Skin disorder (skin disease)
Skin ulcer

male:

Incisional hernia (hernia caused by an incompletely-healed surgical wound)
Renal cancer (cancer of kidney)
Migraine (headache)
Mood swings (an extreme or rapid change in mood)
Night sweats (sweating in night)
Nightmare (unpleasant dream)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Proteinuria (presence of protein in the urine)
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Clindamycin Phosphate and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Discomfort
Drug resistance (reduction in effectiveness of a drug)
Emotional disorder
Emotional distress
Fear

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)
Impaired healing
Influenza like illness
Malaise (a feeling of general discomfort or uneasiness)
Pain
Pyrexia (fever)
Skin disorder (skin disease)
Skin ulcer
Staphylococcal skin infection (skin infection by an infection with staphylococcus bacteria)
White blood cell count decreased

50-59:

Incisional hernia (hernia caused by an incompletely-healed surgical wound)
Renal cancer (cancer of kidney)
Hospitalisation
Pulmonary embolism (blockage of the main artery of the lung)

60+:

Death
Dyspnoea (difficult or laboured respiration)
Haemoglobin decreased
Hypercapnia (too much smoke)
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Pain: 2 people, 18.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
Hepatitis C: 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Hiv Infection: 1 person, 9.09%
Bladder Spasm: 1 person, 9.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 9.09%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 1 person, 9.09%
Constipation: 1 person, 9.09%
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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