Clinoril and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clinoril (sulindac) and Digoxin (digoxin). Common drug interactions include discomfort among females and ventricular fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Clinoril and Digoxin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Clinoril?

Clinoril has active ingredients of sulindac. eHealthMe is studying from 1,521 Clinoril users. Check the latest studies of Clinoril.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Jul, 11, 2026

19 people who take Clinoril and Digoxin together, and have interactions are studied.

What are the common drug interactions of Clinoril and Digoxin, by gender? *:

female:

Discomfort
Drug effect decreased
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Mass
Melaena (the passage of black, tarry stools)
Neuropathy peripheral (surface nerve damage)
Pain
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Vertebral artery occlusion (vertebral artery blockage)

male:

Ventricular fibrillation (abnormally irregular heart rhythm)
Cardiac arrest
Anxiety
Aortic valve incompetence
Arrhythmia (irregular heartbeat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Cardiac failure congestive

What are the common drug interactions of Clinoril and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Flatulence (flatus expelled through the anus)
Headache (pain in head)
Hepatic enzyme increased
Hyperchloraemia (an excess of chlorides in the blood)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)
Leukopenia (less number of white blood cells in blood)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)

60+:

Ventricular fibrillation (abnormally irregular heart rhythm)
Cardiac arrest
Dizziness
Hypertension (high blood pressure)
Ill-defined disorder
Injury
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Loss of consciousness
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal pain upper

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 15.79%
Diabetes: 2 people, 10.53%
Osteoporosis (bones weak and more likely to break): 2 people, 10.53%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Eye Pruritus (eye itching): 1 person, 5.26%
Diarrhea: 1 person, 5.26%
Constipation: 1 person, 5.26%
Colitis (inflammation of colon): 1 person, 5.26%
Cardiac Failure Congestive: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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