Clobazam and Methadose drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clobazam (clobazam) and Methadose (methadone hydrochloride). Common drug interactions include drug dependence among males.
The phase IV clinical study analyzes what interactions people have when they take Clobazam and Methadose. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Clobazam?
Clobazam has active ingredients of clobazam. eHealthMe is studying from 14,399 Clobazam users. Check the latest studies of Clobazam.
What is Methadose?
Methadose has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 5,101 Methadose users. Check the latest studies of Methadose.
16 people who take Clobazam and Methadose together, and have interactions are studied.

What are the common drug interactions of Clobazam and Methadose, by gender? *:
female:
n/a
male:
- Drug dependence
- Respiratory depression (respiration has a rate below 12 breaths)
- Pulmonary congestion (congestion in the lungs)
- Unresponsive to stimuli
- Drug ineffective
- Child abuse
- Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
- Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
- Obesity (having too much body fat)
- Victim of child abuse
What are the common drug interactions of Clobazam and Methadose, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Obesity (having too much body fat)
- Victim of child abuse
- Drug dependence
- Respiratory depression (respiration has a rate below 12 breaths)
- Drug ineffective
- Child abuse
- Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
- Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Depressed level of consciousness
- Dyspnoea (difficult or laboured respiration)
- Pulmonary congestion (congestion in the lungs)
- Unresponsive to stimuli
60+:
n/a
What are the existing conditions these people have? *
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 14 people, 87.50%
- Muscle Spasms (muscle contraction): 14 people, 87.50%
- Itching: 14 people, 87.50%
- Constipation: 14 people, 87.50%
- Back Pain: 13 people, 81.25%
- Child Abuse: 11 people, 68.75%
- Sleep Disorder: 10 people, 62.50%
* Approximation only. Some reports may have incomplete information.
Do you take Clobazam and Methadose?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Clobazam and Methadose:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clobazam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methadose:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clobazam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methadose and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clobazam and methadone hydrochloride (the active ingredients of Clobazam and Methadose, respectively), and Clobazam and Methadose (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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