Clobazam and Singulair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clobazam (clobazam) and Singulair (montelukast sodium). Common drug interactions include seizure among females and child abuse among males.

The phase IV clinical study analyzes what interactions people have when they take Clobazam and Singulair. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Clobazam?

Clobazam has active ingredients of clobazam. eHealthMe is studying from 14,399 Clobazam users. Check the latest studies of Clobazam.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.



On Jul, 11, 2026

90 people who take Clobazam and Singulair together, and have interactions are studied.

Clobazam and Singulair drug interactions.

What are the common drug interactions of Clobazam and Singulair, by gender? *:

female:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Abdominal discomfort
  3. Death
  4. Fatigue (feeling of tiredness)
  5. Nausea (feeling of having an urge to vomit)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Adverse drug reaction
  8. Dyspnoea (difficult or laboured respiration)
  9. Pain in extremity
  10. Psychomotor hyperactivity (feelings of extreme restlessness)

male:

  1. Child abuse
  2. Drug abuse
  3. Obesity (having too much body fat)
  4. Cough
  5. Pyrexia (fever)
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Dementia (madness)
  8. Tenderness (pain or discomfort when an affected area is touched)
  9. Loss of consciousness
  10. Death

What are the common drug interactions of Clobazam and Singulair, by age (0-1 to 60+)? *:

0-1:

  1. Irritability
  2. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  3. Salivary hypersecretion (excess saliva secretion)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

2-9:

  1. Fatigue (feeling of tiredness)
  2. Psychomotor hyperactivity (feelings of extreme restlessness)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Adverse drug reaction
  5. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  6. C-reactive protein increased
  7. Death
  8. Decreased appetite
  9. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  10. Pyrexia (fever)

10-19:

  1. Child abuse
  2. Drug abuse
  3. Drug dependence
  4. Respiratory depression (respiration has a rate below 12 breaths)
  5. Drug ineffective
  6. Victim of child abuse
  7. Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
  8. Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
  9. Obesity (having too much body fat)
  10. Hypersomnia (excessive daytime sleepiness (eds))

20-29:

  1. Death
  2. Acute respiratory failure
  3. Encephalopathy (functioning of the brain is affected by some agent or condition)
  4. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  5. Dyspnoea (difficult or laboured respiration)
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

  1. Anxiety
  2. Bruxism (habitual grinding of the teeth, typically during sleep)
  3. Haemoglobin decreased
  4. Hypersensitivity
  5. Loose tooth
  6. Memory impairment
  7. Pain
  8. Diarrhoea
  9. Drug ineffective
  10. Feeling hot

40-49:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Sensory loss (senses loss)
  3. Skin warm
  4. Skin wrinkling (wrinkle on skin)
  5. Sleep disorder
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  8. Temperature regulation disorder (body is unable to maintain temperature)
  9. Thirst
  10. Throat irritation

50-59:

  1. Asthenia (weakness)
  2. Chest discomfort
  3. Cough
  4. Cystitis (inflammation of the wall of the bladder)
  5. Disability
  6. Dyspnoea (difficult or laboured respiration)
  7. Ear discomfort
  8. Fatigue (feeling of tiredness)
  9. Muscle spasms (muscle contraction)
  10. Muscular weakness (muscle weakness)

60+:

  1. Cough
  2. Fatigue (feeling of tiredness)
  3. Pyrexia (fever)
  4. Urinary tract infection
  5. Dementia (madness)
  6. Death
  7. Headache (pain in head)
  8. Pain in extremity

What are the existing conditions these people have? *

  1. Transplant Rejection (a transplant material is not worked): 26 people, 28.89%
  2. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 18 people, 20.00%
  3. Sleep Disorder: 12 people, 13.33%
  4. Stress And Anxiety: 9 people, 10.00%
  5. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 9 people, 10.00%
  6. High Blood Pressure: 9 people, 10.00%
  7. Angiopathy (generic term for a disease of the blood vessels): 9 people, 10.00%
  8. Pain: 7 people, 7.78%
  9. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 7 people, 7.78%
  10. Itching: 7 people, 7.78%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clobazam and Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clobazam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clobazam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Singulair and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clobazam and montelukast sodium (the active ingredients of Clobazam and Singulair, respectively), and Clobazam and Singulair (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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