Clobex and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clobex (clobetasol propionate) and Ibu (ibuprofen). Common drug interactions include dermatitis bullous among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Clobex and Ibu. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Clobex?

Clobex has active ingredients of clobetasol propionate. It is often used in psoriasis. eHealthMe is studying from 1,447 Clobex users. Check the latest studies of Clobex.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Aug, 08, 2026

44 people who take Clobex and Ibu together, and have interactions are studied.

What are the common drug interactions of Clobex and Ibu, by gender? *:

female:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Nasopharyngitis (inflammation of the nasopharynx)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Affect lability (emotional incontinence)
Atypical femur fracture
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
General physical health deterioration (weak health status)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Overdose
Weight increased
Chronic kidney disease
Emotional distress
Renal impairment (severely reduced kidney function)
Ascites (accumulation of fluid in the abdominal cavity)
Death
Injection site bruising

What are the common drug interactions of Clobex and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Cardiomegaly (increased size of heart than normal)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Emotional distress
General physical health deterioration (weak health status)
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

Abdominal pain
Cholecystitis (infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspepsia (indigestion)
Gallbladder disorder
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Fear of disease
Injury
Myalgia (muscle pain)
Myositis (inflammation of the muscles)
Pulmonary embolism (blockage of the main artery of the lung)
Rash pruritic (redness with itching)

50-59:

Atypical femur fracture
Nasopharyngitis (inflammation of the nasopharynx)
Pain in extremity
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Lip oedema (swelling of lip)
Pruritus (severe itching of the skin)
Tongue oedema (swelling of tongue)
Urticaria (rash of round, red welts on the skin that itch intensely)

60+:

Chronic kidney disease
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Death
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug hypersensitivity
Duodenitis (inflammation of the duodenum)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
General physical health deterioration (weak health status)

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 18.18%
Depression: 4 people, 9.09%
Joint Pain: 3 people, 6.82%
Hypertensive Crisis: 3 people, 6.82%
High Blood Cholesterol: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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