Cloderm and Ketoconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cloderm (clocortolone pivalate) and Ketoconazole (ketoconazole). Common drug interactions include nausea among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Cloderm and Ketoconazole. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cloderm?

Cloderm has active ingredients of clocortolone pivalate. eHealthMe is studying from 176 Cloderm users. Check the latest studies of Cloderm.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.



On Jul, 26, 2026

13 people who take Cloderm and Ketoconazole together, and have interactions are studied.

Cloderm and Ketoconazole drug interactions.

What are the common drug interactions of Cloderm and Ketoconazole, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Diarrhoea
  4. Pelvic pain
  5. Alopecia (absence of hair from areas of the body)
  6. Psoriasis (immune-mediated disease that affects the skin)
  7. Iliac vein occlusion (narrowing of an iliac vein segment between the aortic bifurcation and the groin)
  8. Vomiting
  9. Chronic kidney disease
  10. Decreased appetite

male:

  1. Arthralgia (joint pain)
  2. Dermal cyst
  3. Skin plaque (red, scaly patches to appear on the skin)
  4. Erythema (redness of the skin)
  5. Joint stiffness
  6. Papule
  7. Pruritus (severe itching of the skin)
  8. Psoriasis (immune-mediated disease that affects the skin)
  9. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  10. Skin exfoliation (removal of the oldest dead skin cells)

What are the common drug interactions of Cloderm and Ketoconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Pelvic pain
  3. Iliac vein occlusion (narrowing of an iliac vein segment between the aortic bifurcation and the groin)

50-59:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Alopecia (absence of hair from areas of the body)
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Chronic kidney disease
  6. Renal cancer (cancer of kidney)
  7. Vomiting

60+:

n/a

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 8 people, 61.54%
  2. Birth Control: 4 people, 30.77%
  3. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 30.77%
  4. High Blood Pressure: 4 people, 30.77%
  5. Iliac Vein Occlusion (narrowing of an iliac vein segment between the aortic bifurcation and the groin): 2 people, 15.38%
  6. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 15.38%
  7. Ovarian Cysts (fluid filled sacs of the ovary): 2 people, 15.38%
  8. Menstruation Irregular: 2 people, 15.38%
  9. Depression: 1 person, 7.69%
  10. High Blood Cholesterol: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cloderm and Ketoconazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cloderm and Ketoconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cloderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ketoconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cloderm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clocortolone pivalate and ketoconazole (the active ingredients of Cloderm and Ketoconazole, respectively), and Cloderm and Ketoconazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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