Clofarabine and Micafungin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clofarabine (clofarabine) and Micafungin (micafungin sodium). Common drug interactions include lung infection among females and mental status changes among males.
The phase IV clinical study analyzes what interactions people have when they take Clofarabine and Micafungin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Clofarabine?
Clofarabine has active ingredients of clofarabine. eHealthMe is studying from 2,644 Clofarabine users. Check the latest studies of Clofarabine.
What is Micafungin?
Micafungin has active ingredients of micafungin sodium. eHealthMe is studying from 6,562 Micafungin users. Check the latest studies of Micafungin.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
45 people who take Clofarabine and Micafungin together, and have interactions are studied.

What are the common drug interactions of Clofarabine and Micafungin, by gender? *:
female:
- Lung infection
- Alanine aminotransferase increased
- Anaemia (lack of blood)
- Aspartate aminotransferase increased
- Diarrhoea
- Febrile neutropenia (fever with reduced white blood cells)
- Heart rate increased
- Hypoaesthesia (reduced sense of touch or sensation)
- Pain
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
male:
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Febrile neutropenia (fever with reduced white blood cells)
- Transaminases increased
- Drug ineffective
- Renal failure acute (rapid kidney dysfunction)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Neutropenia (an abnormally low number of neutrophils)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Abdominal distension
What are the common drug interactions of Clofarabine and Micafungin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Anaemia (lack of blood)
- Abdominal pain
- Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
- Aspartate aminotransferase increased
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Cough
- Diarrhoea
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Epistaxis (bleed from the nose)
- Febrile neutropenia (fever with reduced white blood cells)
10-19:
- Hypotension (abnormally low blood pressure)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Acute respiratory distress syndrome
- Blood bilirubin increased
- Hypernatraemia (an abnormally high plasma concentration of sodium ions)
- Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
- Blood sodium increased
- Lung infection
- Blood pressure increased
- Heart rate increased
20-29:
- Sinusitis fungal (fungal infection of sinus)
- Drug ineffective
- Haemodynamic instability (disturbances in the blood movement in our body)
- Hepatotoxicity (chemical-driven liver damage)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Septic shock (shock due to blood infection)
30-39:
- Confusional state
- Diarrhoea
- General physical health deterioration (weak health status)
- Haematemesis (vomiting of blood)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hallucination (an experience involving the perception of something not present)
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Hypotension (abnormally low blood pressure)
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
40-49:
- Capillary leak syndrome (capillary leaks plasma)
- Mucosal haemorrhage (bleeding from mucous membrane)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pleural effusion (water on the lungs)
- Pneumonia
- Pulseless electrical activity
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Culture throat positive
- Culture urine positive
- Dehydration (dryness resulting from the removal of water)
- Escherichia infection (bacterial infection by escherichia coli)
- Febrile neutropenia (fever with reduced white blood cells)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Generalised oedema (swelling all over the body)
- Malignant neoplasm progression (cancer tumour came back)
- Multi-organ failure (multisystem organ failure)
60+:
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Blood creatinine increased
- Cytomegalovirus viraemia (cytomegalo virus in blood stream)
- Electrocardiogram st segment elevation
- Fungaemia (fungi circulate in the blood)
- Haemodynamic instability (disturbances in the blood movement in our body)
- Hypotension (abnormally low blood pressure)
- Muscle fatigue (a condition in which muscles cannot exert their normal force)
- Renal tubular necrosis (death of kidney tubules)
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
What are the existing conditions these people have? *
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 15 people, 33.33%
- Nausea (feeling of having an urge to vomit): 12 people, 26.67%
- Constipation: 11 people, 24.44%
- Bone Marrow Conditioning Regimen: 11 people, 24.44%
- Cough: 9 people, 20.00%
- Pain: 9 people, 20.00%
- Multiple Allergies (allergy to multiple agents): 9 people, 20.00%
- Chills (felling of cold): 9 people, 20.00%
- Dry Skin: 9 people, 20.00%
- Sedation: 9 people, 20.00%
* Approximation only. Some reports may have incomplete information.
Do you take Clofarabine and Micafungin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clofarabine (2,644 reports)
- Micafungin (6,562 reports)
Browse all drug interactions of Clofarabine and Micafungin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clofarabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Micafungin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clofarabine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Micafungin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Cheng HI, Chen TH, Chung TC, Lee HY, Yu CY, "Micafungin-Induced Hyperbilirubinemia: A Case Report", 臺灣臨床藥學雜誌, 2014 Jun .
- Cheng HI, Chen TH, Chung TC, Lee HY, Yu CY, "Micafungin-Induced Hyperbilirubinemia: A Case Report", 臺灣臨床藥學雜誌, 2014 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on clofarabine and micafungin sodium (the active ingredients of Clofarabine and Micafungin, respectively), and Clofarabine and Micafungin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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