Clofarabine and Tramadol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clofarabine (clofarabine) and Tramadol (tramadol hydrochloride). Common drug interactions include ascites among females and photosensitivity reaction among males.
The phase IV clinical study analyzes what interactions people have when they take Clofarabine and Tramadol. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Clofarabine?
Clofarabine has active ingredients of clofarabine. eHealthMe is studying from 2,644 Clofarabine users. Check the latest studies of Clofarabine.
What is Tramadol?
Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.
25 people who take Clofarabine and Tramadol together, and have interactions are studied.

What are the common drug interactions of Clofarabine and Tramadol, by gender? *:
female:
- Ascites (accumulation of fluid in the abdominal cavity)
- Capillary leak syndrome (capillary leaks plasma)
- Dyspnoea (difficult or laboured respiration)
- Hyperglycaemia (high blood sugar)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Disease progression
- Death
male:
- Photosensitivity reaction
- Febrile neutropenia (fever with reduced white blood cells)
- Capillary leak syndrome (capillary leaks plasma)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Constipation
- Disease complication
- Gait disturbance
- Gastric antral vascular ectasia (blood vessels in the lining of the stomach become fragile and become prone to rupture and bleeding)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
What are the common drug interactions of Clofarabine and Tramadol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Dyspnoea (difficult or laboured respiration)
- Hyperglycaemia (high blood sugar)
- Febrile neutropenia (fever with reduced white blood cells)
10-19:
- Lung disorder (lung disease)
20-29:
- Photosensitivity reaction
- Burning sensation
- Dry skin
- Papule
- Skin exfoliation (removal of the oldest dead skin cells)
- Skin lesion
30-39:
n/a
40-49:
n/a
50-59:
- Bacteraemia (presence of bacteria in the blood)
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Constipation
- Dry skin
- Febrile neutropenia (fever with reduced white blood cells)
- Gastric antral vascular ectasia (blood vessels in the lining of the stomach become fragile and become prone to rupture and bleeding)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Headache (pain in head)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
60+:
- Activities of daily living impaired
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Pancreatitis (inflammation of pancreas)
- Pneumonia
- Speech disorder
- Tremor (trembling or shaking movements in one or more parts of your body)
- Capillary leak syndrome (capillary leaks plasma)
What are the existing conditions these people have? *
- Cholangitis (infection of the bile duct): 7 people, 28.00%
- Bone Marrow Conditioning Regimen: 7 people, 28.00%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 28.00%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 16.00%
- Haematemesis (vomiting of blood): 3 people, 12.00%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 12.00%
- Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 3 people, 12.00%
- Fever: 3 people, 12.00%
- Febrile Neutropenia (fever with reduced white blood cells): 3 people, 12.00%
- Electrolyte Imbalance: 3 people, 12.00%
* Approximation only. Some reports may have incomplete information.
Do you take Clofarabine and Tramadol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clofarabine (2,644 reports)
- Tramadol (235,798 reports)
Browse all drug interactions of Clofarabine and Tramadol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clofarabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tramadol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clofarabine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tramadol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clofarabine and tramadol hydrochloride (the active ingredients of Clofarabine and Tramadol, respectively), and Clofarabine and Tramadol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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