Clonidine hydrochloride and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clonidine hydrochloride (clonidine hydrochloride) and Digoxin (digoxin). Common drug interactions include nausea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Clonidine hydrochloride and Digoxin. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Clonidine hydrochloride?

Clonidine hydrochloride has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,643 Clonidine hydrochloride users. Check the latest studies of Clonidine hydrochloride.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Aug, 03, 2026

27 people who take Clonidine hydrochloride and Digoxin together, and have interactions are studied.

Clonidine hydrochloride and Digoxin drug interactions.

What are the common drug interactions of Clonidine Hydrochloride and Digoxin, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Oral disorder (mouth disease)
Pain
Pain in extremity
Pancreatic mass
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Poor quality sleep
Pruritus (severe itching of the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Renal failure (kidney dysfunction)

male:

Chronic kidney disease
Diarrhoea
Haemorrhage intracranial (bleeding within the skull)
Interstitial lung disease
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Anaemia (lack of blood)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chills (felling of cold)
Constipation

What are the common drug interactions of Clonidine Hydrochloride and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective

40-49:

Renal failure (kidney dysfunction)

50-59:

Renal injury (kidney injury)
Sacral pain (pain at sacrum bone region)
Sinusitis (inflammation of sinus)
Skin infection
Somnolence (a state of near-sleep, a strong desire for sleep)
Spinal stenosis (narrowing of spinal column)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tenderness (pain or discomfort when an affected area is touched)
Urinary tract infection
Wound infection

60+:

Chronic kidney disease
Acute respiratory failure
Renal failure (kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Haemorrhage intracranial (bleeding within the skull)
Interstitial lung disease
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Anaemia (lack of blood)
Arthralgia (joint pain)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 14.81%
Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Thyroid Diseases: 2 people, 7.41%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 7.41%
Stress And Anxiety: 2 people, 7.41%
Oedema Peripheral (superficial swelling): 2 people, 7.41%
Infection: 2 people, 7.41%
Immune System Disorder: 2 people, 7.41%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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