Clozapine and Nardil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clozapine (clozapine) and Nardil (phenelzine sulfate). Common drug interactions include blood cholesterol increased among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Clozapine and Nardil. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

What is Nardil?

Nardil has active ingredients of phenelzine sulfate. It is often used in depression. eHealthMe is studying from 2,327 Nardil users. Check the latest studies of Nardil.

On Jul, 25, 2026

11 people who take Clozapine and Nardil together, and have interactions are studied.

What are the common drug interactions of Clozapine and Nardil, by gender? *:

female:

Blood cholesterol increased
Obesity (having too much body fat)
Renal failure (kidney dysfunction)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Type 2 diabetes mellitus
Neutropenia (an abnormally low number of neutrophils)

male:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Oxygen saturation decreased
Drug effect decreased
Fatigue (feeling of tiredness)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hypersomnia (excessive daytime sleepiness (eds))
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Impaired work ability
Malaise (a feeling of general discomfort or uneasiness)
Muscle rigidity (muscle stiffness)

What are the common drug interactions of Clozapine and Nardil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Oxygen saturation decreased
Tonic clonic movements (generalized seizure that affects the entire brain)
Blood cholesterol increased
Obesity (having too much body fat)
Renal failure (kidney dysfunction)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Type 2 diabetes mellitus
Neutropenia (an abnormally low number of neutrophils)

50-59:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Muscle tightness
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Panic disorder
Difficulty in walking
Fatigue (feeling of tiredness)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)

60+:

n/a

What are the existing conditions these people have? *

Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 5 people, 45.45%
Ill-Defined Disorder: 3 people, 27.27%
Post-Traumatic Stress Disorder: 2 people, 18.18%
Insomnia (sleeplessness): 2 people, 18.18%
Bipolar Disorder (mood disorder): 2 people, 18.18%
Panic Disorder: 1 person, 9.09%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 9.09%
Delusion (a false belief or opinion): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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