Clozaril and Entacapone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clozaril (clozapine) and Entacapone (entacapone). Common drug interactions include dementia with lewy bodies among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Clozaril and Entacapone. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Clozaril?

Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.

What is Entacapone?

Entacapone has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 4,261 Entacapone users. Check the latest studies of Entacapone.

On Jul, 14, 2026

23 people who take Clozaril and Entacapone together, and have interactions are studied.

Clozaril and Entacapone drug interactions.

What are the common drug interactions of Clozaril and Entacapone, by gender? *:

female:

Dementia with lewy bodies (progressive degenerative disease or syndrome of the brain)
Immobile (not moving)
Pneumonia
Terminal state (the transitional states between life and biological death)
Adverse event
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Hallucination, visual (seeing things that aren't there)
Hypophagia (reduced food intake)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Psychotic disorder

male:

White blood cell count decreased
Rib fracture
Urinary retention (the inability to completely or partially empty the bladder)
Constipation
Abnormal behaviour
Aggression
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Delusion (a false belief or opinion)
Emotional distress
Fall

What are the common drug interactions of Clozaril and Entacapone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Decreased appetite
General physical health deterioration (weak health status)
Irritability
Mobility decreased (ability to move is reduced)
Myocarditis (inflammation of heart muscle myocardium)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

50-59:

White blood cell count decreased
Platelet count decreased
Anaemia (lack of blood)
Gamma-glutamyltransferase decreased
Neutropenia (an abnormally low number of neutrophils)
Urinary retention (the inability to completely or partially empty the bladder)
Constipation
Drug intolerance (drug sensitivity)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Pneumonia
Hallucination, visual (seeing things that aren't there)
Abnormal behaviour
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Delusion (a false belief or opinion)
Emotional distress
Fall
Fatigue (feeling of tiredness)
Hypoxia (low oxygen in tissues)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)

What are the existing conditions these people have? *

Psychotic Disorder: 10 people, 43.48%
Constipation: 5 people, 21.74%
Depression: 4 people, 17.39%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 13.04%
Stress And Anxiety: 2 people, 8.70%
Pain: 2 people, 8.70%
Dementia With Lewy Bodies (progressive degenerative disease or syndrome of the brain): 2 people, 8.70%
Dementia (madness): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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