Clozaril and Yaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clozaril (clozapine) and Yaz (drospirenone; ethinyl estradiol). Common drug interactions include skin disorder among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Clozaril and Yaz. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Clozaril?

Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

On Jul, 13, 2026

17 people who take Clozaril and Yaz together, and have interactions are studied.

What are the common drug interactions of Clozaril and Yaz, by gender? *:

female:

Skin disorder (skin disease)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombocytosis
Vomiting
White blood cell disorder
Breast cancer
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Febrile neutropenia (fever with reduced white blood cells)
Hyperhidrosis (abnormally increased sweating)

male:

Pain
Injury
Aggression
Arthralgia (joint pain)
Burkitt's lymphoma (cancer of the lymphatic system)
Coma (state of unconsciousness lasting more than six hours)
Delirium (wild excitement)
Emotional distress
Fear
Gallbladder disorder

What are the common drug interactions of Clozaril and Yaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Urinary tract infection
Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Dementia (madness)
Dyspnoea (difficult or laboured respiration)
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Gallbladder disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Infection
Lymphoma (cancer that begins in immune system cells)

30-39:

Injury
Constipation
Cholecystitis chronic (long lasting infection of gallbladder)
Fatigue (feeling of tiredness)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal distension
Anxiety
Depression
Diarrhoea
Dyspepsia (indigestion)

40-49:

Prostate cancer
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Asthenia (weakness)
Brain neoplasm (tumour of brain)
Death
Emotional distress
General physical health deterioration (weak health status)
Injury
Loss of consciousness

50-59:

Breast cancer
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Febrile neutropenia (fever with reduced white blood cells)
Neoplasm malignant (cancer tumour)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Pulmonary embolism (blockage of the main artery of the lung)
White blood cell count decreased
White blood cell count increased

60+:

Burkitt's lymphoma (cancer of the lymphatic system)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
White blood cell count increased
Injury
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Pain
Platelet count decreased
Venous injury

What are the existing conditions these people have? *

Pain: 3 people, 17.65%
Depression: 3 people, 17.65%
Acne (skin problems that cause pimples): 2 people, 11.76%
Back Pain: 2 people, 11.76%
Multiple Allergies (allergy to multiple agents): 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%
Urinary Tract Infection: 1 person, 5.88%
High Blood Cholesterol: 1 person, 5.88%
Asthma: 1 person, 5.88%
Bipolar Disorder (mood disorder): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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